While mainstream media and the publishing industry are grappling with the challenges of the digital age, the hugely profitable business of scientific publishing seems to be going from strength to strength. With more than more than 28,000 science journals published today, the industry brings in total global revenues of more than $30 billion. That puts the industry between the music and film industries in total size, but what is the real cost to science? Stephen Buranyi has written about the business of science publishing for The Guardian, amid questions over the current commercial model.