This Week In Startups is made possible by:

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Today’s show: 

Sean Liu gave his OpenClaw “eyes” by hooking the AI assistant up to his Meta Ray Bans. While Jason and Alex consider the implications… guest expert Alex Finn quickly loses interest…

It’s another All-Clawdbot TWiST where we debate the most essential uses for the viral agent platform. For their part, Alex Finn and Matt Van Horn are building practical skills to help founders (esp. solo founders)… Alex has a brain trust of AI agents working round the clock to improve his organization and content, while Matt designed a skill for his agent to order sushi lunches (keeping them under $20).

PLUS find out how Producer Oliver designed his “Model Council” based on Perplexity’s set-up, why running everything local is “illogical” for most people in 2026, AND why Jason’s next Founder U cohort will all be building with OpenClaw.

Timestamps: 

(00:00) Why Jason is STILL Claw-pilled! We can’t get enough!

(03:17) “Mr. Clawdbot” Alex Finn of Creator Buddy joins us! He’s Claw-Pilled too!

(04:50) Sean Liu (@_seanliu) added OpenClaw to his Meta Ray Bans… Here’s why Alex doesn’t care!

(8:33) Lost your job to AI? Maybe AI can make you a founder!

(12:35) LinkedIn Jobs - Hire right, the first time. Post your first job and get $100 off towards your job post at http://linkedin.com/twist Terms and conditions apply.

(13:34) “Last 30 Days” skill creator Matt Van Horn (@mvanhorn) joins the show

(14:54) Why Jason wants to invest in Matt’s new project.

(15:53) Meeting Alex’s organization of AI agents who collaborate on his projects autonomously

(22:28) Is Alex planning to turn his OpenClaw set-up into a company? Maybe…

(23:10) Every.io - For all of your incorporation, banking, payroll, benefits, accounting, taxes or other back-office administration needs, visit http://every.io/

(25:16) Using OpenClaw to create a “lights out” startup

(28:17) Deciding when to use local models vs. more powerful cloud-based models

(29:52) Northwest Registered Agent. Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity —  Learn more at www.northwestregisteredagent.com/twist

(30:58) How Producer Oliver created a “Model Council” for LAUNCH based on Perplexity’s set-up

(35:52) Why it’s so important to have an orchestrator that knows the right model for the right task

(39:12) Why running everything local is “illogical” for most companies in 2026

(41:15) Matt walks us through the latest and greatest incarnation of his “Last 30 Days” skill

(45:57) Why Jason thinks recursive machine learning is the solution to human laziness

(46:38) How Alex has supercharged his social media and his startup during OpenClaw Mania

(50:15) Why Founder University is going ALL OPENCLAW next cohort

(51:21) How big a jump over Opus 4.5 is Opus 4.6?

(53:35) OpenClaw’s going to start scanning skills for malware… Will this help?

(57:13) No one was SUPER impressed by the AI dot com Super Bowl ad… except JCal

(1:01:11) Matt used his “Order Sushi” OpenClaw skill live on the show to get lunch

(1:04:08) Polymarket’s sharps are wagering on Claude 5’s hotly anticipated release

Thank you to our partners:

(12:35) LinkedIn Jobs - Hire right, the first time. Post your first job and get $100 off towards your job post at http://linkedin.com/twist Terms and conditions apply.

(23:10) Every.io - For all of your incorporation, banking, payroll, benefits, accounting, taxes or other back-office administration needs, visit http://every.io/

(29:52) Northwest Registered Agent. Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity —  Learn more at www.northwestregisteredagent.com/twist

Check out all our partner offers: https://partners.launch.co/

This Week In Startups is made possible by:

Crusoe Cloud - https://crusoe.ai/savings

Lemon IO - https://Lemon.io/twist

Northwest Registered Agent - https://www.northwestregisteredagent.com/twist

Thanks to our guests:

Alex Cheema of ExoLabs http://exolabs.net

Ryan Yanneli of NextVisit https://nextvisit.ai/

Today’s show: 

It’s the Age of Ultron at TWiST and LAUNCH. We’ve given our OpenClaw digital Replicants the keys to all of our systems and we’re seeing how much of our jobs they can really do when left to their own devices.

Producer Oliver stops by the show to give us a peek behind the curtain, at the new control panel and dashboard OpenClaw built FOR ITSELF (with a bit of human assistance).

PLUS we’re joined by Alex Cheema of ExoLabs. His company helps everyday consumers run powerful frontier LLMs on their own devices, essential to protect your data and personalize your AI experience.

ALSO congratulations to Ryan Yanneli from NextVisit on winning our Gamma Pitch Deck Competition! He walks away with $25K from LAUNCH and our friends at Gamma.

Timestamps:

(00:00) Introducing Alex Cheema to the show

(3:17) Why it is so important to run AI on local hardware

(6:58) Using OpenClaw Producer to automate TWiST

(8:59) How to Train your AI

(11:58) What is a Chron Job? (Hint: chron means chronological)

(13:24) Crusoe Cloud: Crusoe is the AI factory company. Reliable infrastructure and expert support. Visit https://crusoe.ai/savings to reserve your capacity for the latest GPUs today.

(17:53) OpenClaw managing the LAUNCH/TWiST team

(19:54)  Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist

(20:58) Turning AI into Ultron, self optimization

(27:21) The Future: frontier models: running on your Iphone!

(28:37) Prompt injections: how people can hack your OpenClaw

(30:25) Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity —  Learn more at https://www.northwestregisteredagent.com/twist

(31:31) OpenClaw invites guests that join the show

(40:29) Oliver shows off OpenClaw mission control dashboard

(46:30) Stacking Apple Silicon vs. Running Kimi-K

(50:18) How Exo Labs works — stringing together Mac Silicon

(54:29) Ryan from Nextvisit wins Gamma Pitch Competition

(59:10) Industry Season 4 reflects tech regulation

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(13:24) Crusoe Cloud: Crusoe is the AI factory company. Reliable infrastructure and expert support. Visit https://crusoe.ai/savings to reserve your capacity for the latest GPUs today.

(19:54)  Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist

(30:25) Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity —  Learn more at https://www.northwestregisteredagent.com/twist

Check out all our partner offers: https://partners.launch.co/

This Week In Startups is made possible by:

Circle - http://Circle.so/twist

Caldera Lab - http://calderalab.com/TWIST

LinkedIn - http://linkedin.com/twist

Today’s show: 

There was a time, not long ago, when offices everywhere came to a standstill, and everyone became even more fixated on their phones than usual, each time HQ Trivia went live. The app-based game show was a massive viral hit… until suddenly, around a year later, it wasn’t.

Now, HQ Trivia host Scott Rogowsky is back with a new concept: Savvy, another game show you play on your phone, this time inspired by the word puzzle hit Wordle. Is lightning about to strike twice? 

PLUS, Alex chats with Trevor Bennett of space transportation outfit Starfish Space. This comes off two major successes for the team: the Remora mission that proved Stafish’s autonomous rendezvous capabilities and the $52.5 Million dollar contract to dispose of low Earth orbit satellites.

Timestamps: 

(00:00) How Scott first got involved with HQ Trivia

(2:23) Why Scott thinks HQ Trivia struck such a chord with fans

(4:12) Scott couldn’t get a job in late night, so he made his own show

(5:31) Delving into the behind-the-scenes tensions at HQ Trivia

(11:07) Circle -  the easiest way to build a home for your community, events, and courses — all under your own brand. TWiST listeners get $1,000 off the Circle Plus Plan by going to http://Circle.so/twist

(13:53) The end of HQ Trivia and why Scott jumped ship

(16:35) Savvy just had its series premiere: you play the game against the host

(20:14) How to play Savvy and win cash

(20:57) Why Jason thinks a subscription model is the future of Savvy

(22:25) Whether you’re starting fresh or upgrading your routine, Caldera Lab makes skincare simple and effective. Head to http://calderalab.com/TWIST and use TWIST at checkout for 20% off your first order.

(23:31) Introducing Dr. Trevor Bennet of Starfish Space

(24:04) What the Otter Spacecraft does: de-orbiting to clean up space

(26:46) Why space will need hundreds of Otters in space

(29:24) LinkedIn Jobs - Hire right, the first time. Post your first job and get $100 off towards your job post at http://linkedin.com/twist Terms and conditions apply.

(30:23) Starfish Space’s business model: operating a starfleet

(33:17) The success of the Remora mission: autonomous rendezvous in space.

(43:47) The rise of the space economy

(48:18) Starfish’s $52.5 Million dollar contract and what it means for the space ecosystem

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Thank you to our partners:

(11:07) Circle -  the easiest way to build a home for your community, events, and courses — all under your own brand. TWiST listeners get $1,000 off the Circle Plus Plan by going to http://Circle.so/twist

(22:25) Whether you’re starting fresh or upgrading your routine, Caldera Lab makes skincare simple and effective. Head to http://calderalab.com/TWIST) and use TWIST at checkout for 20% off your first order.

(29:24) LinkedIn Jobs - Hire right, the first time. Post your first job and get $100 off towards your job post at http://linkedin.com/twist Terms and conditions apply.

Check out all our partner offers: https://partners.launch.com

This Week In Startups is made possible by:

Quadratic - http://quadratic.ai/twist

Today’s show: 

Don’t get distracted! Here are the MOST CRUCIAL aspects of running a startup, where founders need to keep their full and uninterrupted focus.

- Make sure you’re saving up your cash

- Why you need to just get started and build SOMETHING

- Trust and reliability is EVERYTHING for new products

- Why distribution should be your top priority

Download all this practical and tactical startup advice from seasoned veterans Jason Calacanis, Amanda Bradford, and William P. Barnes in this Tokyo edition of TWiST.

Timestamps:

(00:00) Amanda and Will’s big takeaways from Founder U in Saudi Arabia and now Tokyo

(3:19) Why cash flow management is so important before you find PMF

(5:57) Why first-time founders get the order of operations wrong

(6:45) Just build SOMETHING, even if it’s taped together

(11:19) “Focus is everything in the early stages”

(14:17) From a wedge to a bridge

(15:50) Quadratic - Bringing the productivity boost of AI into your spreadsheets. Visit http://quadratic.ai/twist to sign up and use the code TWIST to get one free month of their pro tier subscription.

(18:45) What to put on your “Not Right Now” list

(19:11) Embracing simplicity

(22:00) The importance of trust and reliability (especially for Uber!)

(28:12) Why innovation needs a constraining variable

(33:40) To really drive word of mouth, you have to overdeliver

(36:32) Distribution is the primary job of a founder/CEO

(38:19) Some of the panel’s favorite distribution hacks

(45:54) Why Jason respects Japan’s commitment to excellence and competency

(49:38) Looking for “high slope” in early employees

(53:11) Transitioning your team from early-stage startup to growth

(57:45) Whoever writes it down gets credit for the idea

(58:04) Q: Has the meaning of money changed for the panel now that they’ve had successful exits?

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(15:50) Quadratic - Bringing the productivity boost of AI into your spreadsheets. Visit http://quadratic.ai/twist to sign up and use the code TWIST to get one free month of their pro tier subscription.

Check out all our partner offers: https://partners.launch.co/

This Week In Startups is made possible by:

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Today’s show: 

SpaceX is buying xAI, forming a mega-corp that plans to launch data centers into SPACE. Will Tesla also join up, fulfilling Elon’s destiny to become real-life Tony Stark, with his own Musk Industries? Jason and Alex break down the future of SpaceXAI in a breaking news report.

THEN, we’re still celebrating OpenClaw (née Clawdbot) Mania! Oliver and Lukas return to TWiST to share their Almost Top 10 (okay it’s just a Top 6) favorite Skills so far. 

Learn how they’re using Replicants to summarize TWiST episodes, surf Reddit, produce original Gamma decks, train agents to make themselves smarter, and take care of LAUNCH’s administrative and operations tasks.

Timestamps:

(00:00) BREAKING: SpaceX bought xAI!

 (1:56) Why it will be cheaper to generate compute in space than here on Earth

(8:19) Will Tesla eventually join the club, forming “Musk Industries”?

(11:36) Uber AI Solutions - Your trusted partner to get AI to work in the real world. Book a demo with them TODAY at http://uber.com/twist

(12:37) ALSO BREAKING: We’re still obsessing about Clawdbot/OpenClaw

(14:58) So is OpenClaw and all of its various skills secure yet? NO.

(16:42) Today we’re looking at our picks for the Top 6 OpenClaw skills

(17:13) Alex’s first pick: Reddit (read only), which makes it easier to track down what you want on the aggregator

(19:35) Reddit hates bots! But maybe they’ll change their tune?

(21:47) Deel - Founders ship faster on Deel. Set up payroll for any country in minutes and get back to building. Visit http://deel.com/twist to learn more.

(22:46) Our Replicant summarized the last few episodes of TWiST… but at what COST? (18 cents)

(26:40) Lukas taught our Replicant to make Gamma decks for us

(29:23) Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity —  Learn more at https://www.northwestregisteredagent.com/twist

(30:21) Our Replicant has ALL the Polymarket data now! The power!

(34:14) AI agents are also playing cards together on ClawPoker

(35:07) Oliver tested out our pal Matt Van Horn’s (@mvanhorn) self-improving “Last 30 Days” skill

(38:22) Why memory is so crucial for getting models to improve themselves over time

(40:33) Yo dawg I know you like monitoring tasks so I built you a task monitor that monitors your tasks so you can task monitor your tasks

(41:40) What makes OpenClaw so powerful is also what makes it dangerous!

(49:12) If you want to really learn about OpenClaw, you need to make your own skills

(50:03) Jason’s advice for OpenClaw’s suddenly famous creator: Peter Steinberger (@steipete)

(56:31) What would be the best way(s) to monetize OpenClaw?

(57:54) Will an OpenClaw agent sue a human in court?

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(11:36) Uber AI Solutions - Your trusted partner to get AI to work in the real world. Book a demo with them TODAY at http://uber.com/twist

(21:47) Deel - Founders ship faster on Deel. Set up payroll for any country in minutes and get back to building. Visit http://deel.com/twist to learn more.

(29:23) Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity —  Learn more at https://www.northwestregisteredagent.com/twist

Check out all our partner offers: https://partners.launch.co/

This Week In Startups is made possible by:

Deel - http://deel.com/twist

LinkedIn Jobs - http://linkedin.com/twist

Northwest Registered Agent - https://www.northwestregisteredagent.com/twist

Today’s show: 

On Today’s action packed episode of This Week in Startups, our team is going full AI!

Jason is joined by Oliver Korzen and Lukas Durand from the LAUNCH team, alongside Rahul Sood, founder/CEO of Irrevernt Labs and founder of Voodoo PC.

With the rise of Clawdbot/Moltbot, the question on everyone’s mind is how fast, how much and how safe! Lukas and Oliver show off the ways that This Week in Startups are automating the hours of research and administrative tasks that take up our days and the what this means for running a podcast and venture firm.

Timestamps:

(00:00) Why we’re so obsessed with OpenClaw (Clawdbot)

(00:47) LAUNCH’s own Lukas Durand has joined the pod for the first time… Here’s how he and Jason met…

(02:26) Oliver is also here… check out his new series, This Week in AI

(03:11)How LAUNCH has its OpenClaw bot set up (without all the details!!!)

(06:03) The first few services that LAUNCH authenticated with our OpenClaw… And why!

(6:59) How OpenClaw is helping Oliver to book the show

(11:06) Deel - Founders ship faster on Deel. Set up payroll for any country in minutes and get back to building. Visit http://deel.com/twist to learn more.

(14:08) Why OpenClaw sometimes struggles with context and memory, and how to work around it

(16:03) Understanding how to set up “cron jobs”

(20:19) LinkedIn Jobs - Hire right, the first time. Post your first job and get $100 off towards your job post at http://linkedin.com/twist That’s http://linkedin.com/twist. Terms and conditions apply.

(22:23) How OpenClaw works as our virtual podcast producer, and how much time we’ll save

(24:40) Can OpenClaw also help us prep the podcast agenda (aka THE DOCKET)?

(28:32) Lon chimes in to talk about how Claude helped him prep Jason’s Davos interviews

(31:30) Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity —  Learn more at www.northwestregisteredagent.com/twist

(32:28) How many “Replicants” or AI agents does one company really need?

(36:09) Why Jason asked his OpenClaw bots to self-report on what they’re learning

(37:14) What OpenClaw WON’T do… Where did these guardrails come from?

(39:44)The hardware side… How much of this can you do from a Mac Studio?

(43:29) Zombie Staffers: How OpenClaw can “revive” long-lost employees…

(48:09) We’re putting OpenClaw in charge of the TWiST 500

(51:18) Rahul Sood joins us to talk about the dangers of OpenClaw and how to stay protected

(53:01) Why so many OpenClaw skills have major vulnerabilities

(1:00:00) Moltbook: Where bots hang out with other bots and share info

(1:06:44) Why powerful AI agents will make creative work by humans so much more important.

(1:07:22) Rahul’s final recommendations for max possible OpenClaw security

(1:14:00) Is OpenClaw going to bring hiring to a halt?

(1:21:10) Why getting comfortable with AI tools will become essential for every employee

Thank you to our partners:

(11:06) Deel - Founders ship faster on Deel. Set up payroll for any country in minutes and get back to building. Visit http://deel.com/twist to learn more.

(20:19) LinkedIn Jobs - Hire right, the first time. Post your first job and get $100 off towards your job post at http://linkedin.com/twist That’s http://linkedin.com/twist. Terms and conditions apply.

(31:30) Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity —  Learn more at www.northwestregisteredagent.com/twist

Check out all our partner offers: https://partners.launch.co/

This Week In Startups is made possible by:

Gusto - http://Gusto.com/twist

Zite - http://zite.com/twist

Circle.so - http://circle.so/twist

Guest links: 

Andrew Duffy, Founder and CEO, http://sparkplug.app — Retail incentives and brand partnerships platform

Ford Smith, Founder of http://Ultranative.com — Investing in transformative startups

Socrates Rosenfeld, Founder and CEO of http://iheartjane.com — One stop shop for cannabis products

Today’s show: 

On TWiST’s first Cannabis Roundtable, Jason is joined by three top Cannabis founders and investors: Ford Smith of Ultranative, Andrew Duffy of Sparkplug, and Socrates Rosenfeld of Jane.

How will the regulatory environment and the move to Schedule III change the industry? Are those regulations shaping consumption? How are investors thinking about cannabis startups given the difficulty with exits? Most importantly, what’s the deal with the increasing potency of cannabis?

Each guest has their own perspective, Andrew sees it as a natural reaction from CPG brands to power users, Ford points to “flyover” operators unconcerned with long-term health of the industry, while Socrates refers to moonshine drinking during the prohibition to say that regulations create these problems.

Speaking of moonshine, alcohol consumption is dropping dramatically among Gen-Z, with many pointing to cannabis consumption as a substitute. Some perceive cannabis as healthier and lacking caloric nature of alcohol, which could explain why there are now more daily smokers than daily drinkers!

Timestamps:

(0:00) Guest Introductions for the Cannabis Roundtable!

(2:50) Why Jason invested in Sparkplug

(6:44) How Ford Smith got into Cannabis investing — is it Cannabis a good investment?

(11:40) Gusto - Check out the online payroll and benefits experts with software built specifically for small business and startups. Try Gusto today and get three months FREE at http://Gusto.com/twist.

(12:46) Socrates breaks down building a major cannabis marketplace

(18:13) Canadian legalization and tailwinds for cannabis.

(20:25) How Cannabis startups are pivoting to deal with high competition and regulatory pressure

(21:47) Zite - Zite is the fastest way to build business software with AI. Go to http://zite.com/twist to get started.

(27:07) Who benefits from legalization of cannabis? Healthcare? Retail? Banking?

(28:03) How the alcohol industry is getting crushed by cannabis usage

(31:27) Circle.so -  The easiest way to build a home for your community, events, and courses — all under your own brand. TWiST listeners get $1,000 off Circle’s Professional Plan by going to http://circle.so/twist.

(32:47) Is new cannabis too potent? Is high potency cannabis a result of illegal rules.

(42:05) Why heavy consumers are driving CPG startups to high doses

(44:14) Cannabis psychosis and the problem with brands selling potency items.

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Thank you to our partners:

(11:40) Gusto - Check out the online payroll and benefits experts with software built specifically for small business and startups. Try Gusto today and get three months FREE at http://Gusto.com/twist.

(21:47) Zite - Zite is the fastest way to build business software with AI. Go to http://zite.com/twist to get started.

(31:27) Circle.so -  The easiest way to build a home for your community, events, and courses — all under your own brand. TWiST listeners get $1,000 off Circle’s Professional Plan by going to http://circle.so/twist.

Check out all our partner offers: https://partners.launch.co/

This Week In Startups is made possible by:

Quo - http://quo.com/TWiST

Lemon IO - https://lemon.io/twist

Northwest Registered Agent - https://www.northwestregisteredagent.com/twist

Today’s show: 

Jason is back from Davos and Tokyo! We are jumping right back in with a group of Clawdbot power users: Alex Finn, Matt Von Horn, and Dan Penguine.

Clawdbot is a hot open source AI project that lets users automate… everything! Dan helped his automate his aging parent’s tea shop, Matt built news sourcing bots, and Alex runs his one-man SAAS startup with Clawdbot as an AI employee!

But with all of that power comes the responsibility of making sure you are not giving your AI too many authorizations that could come under fire! Whether fisching emails, “injections”, or bad decision making from incorrect information online.

Check out how these 3 experts, Jason and Alex are thinking about the bleeding edge of AI!

Timestamps:

(00:00) Introducing today’s Clawdbot experts!

(04:09) How Matt Von Horn makes “Skills” with Clawdbot

(10:53) Quo (formerly OpenPhone) gives you a clean, modern way to handle every customer call, text, and thread all in one place. Try it free at http://quo.com/TWiST.

(13:25) Dan Penguine’s “Normy” use case: automating his parent’s tea shop

(19:50) Lemon.io - Get 15% off your first 4 weeks of developer time at https://lemon.io/twist

(22:23) Alex Finn breaks down how Clawdbot lets him run a one man startup

(24:28) Alex Finn on Clawdbot autonomously building apps within his business

(28:33) Security concerns with Clawdbot, can your AI get hacked?

(32:46) Northwest Registered Agent. Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity —  Learn more at https://www.northwestregisteredagent.com/twist

(35:07) Why is everyone buying Mac Minis?

(37:39) How to think about LLM Token usage

(46:02) Clawdbot will build CRMs, project management software, etc without being asked. Is this the end of SAAS?

(46:58) Matt live uploads his new Clawdbot skill on aire!

(48:22) Why was Clawdbot able to move so much quicker than Anthropic and OpenAI?

(50:17) What is Clawdbot’s business model as an open source AI?

(53:27) Matt’s recursive AI prompt loop and how AI prompts layer

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Today’s show:

One day soon, you might consult an AI general practitioner about your health, and then the computer will recommend human specialists to take up your case.

On TWiST Tokyo, Jason chats with Fred Almeida — founder and CEO of American Medical Intelligence Inc. — and Maxwell Weiss, a partner at Pacific Bays Capital.

Together, they discuss the future of medicine, and the opportunities for individuals to take greater control over their health and preventative care strategies.

PLUS a look at how Japan has stayed at the forefront of technology despite NOT being a manufacturing hub, why so many Americans are willing to take a pay cut to move to Japan for work, and the concept of “genten shugi,” and how it prevents some Japanese people from communicating with English speakers, despite understanding the language.

THEN we hear pitches from some of our favorite Founder University x Japan companies, and Fred, Jason, and Max pick their favorites!

Timestamps:

(00:00) Introducing today’s big guests: founder Fred Almeida and investor Max Weiss!

(5:43) Why Fred thinks one day soon, an AI will be your general practitioner

(8:26) The power of getting self-directed medical diagnostics

(13:27) Max says Japan has moved into Decade 2 in its venture capital journey

(14:37) Sentry - New users can get $240 in free credits when they go to sentry.io/twist and use the code TWIST

(16:05) Max and Jason had wagyu barbecue the other night

(17:10) Japan doesn’t OFFICIALLY have a standing army…

(21:37) Why the line between talking startups and politics is blurring

(23:05) Hubspot - Check out the guide “Advanced ChatGPT Prompt Engineering: From Basic to Expert in 7 Days.” Download it for free at clickhubspot.com/twist2.

(24:59) Japan doesn’t make a lot of things, but it produces the underlying tech behind a lot of things

(25:52) Understanding Genten Shugi: Why some in Japan still have an “English allergy”

(29:42) Why some Americans will take a pay cut to come work in Japan

(33:28) Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at www.northwestregisteredagent.com/twist

(34:10) PITCH #1: Cascade(36:10) PITCH #2: Altsource Global(38:10) PITCH #3: GoalMochi(40:25) Jason, Max, and Fred give feedback on our first three pitches(42:45) Would GoalMochi ever consider adding personas for added expertise, like say a nutritionist?(44:30) How does Cascade plan to compete against the massive ad networks of companies like Google and Meta?(46:05) PITCH #4: RandomChat(48:10) PITCH #5: Eir(50:05) More feedback for our final two pitches of the day(52:44) Fred wants to know how Eir’s product will integrate with other systems(54:19) Why Gigi made herself available to chat in her app(57:50) Why Jason thinks RandomChat should add anonymous personas

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Thank you to our partners:

(14:37) Sentry - New users can get $240 in free credits when they go to sentry.io/twist and use the code TWIST

(23:05) Hubspot - Check out the guide “Advanced ChatGPT Prompt Engineering: From Basic to Expert in 7 Days.” Download it for free at clickhubspot.com/twist2.

(33:28) Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at www.northwestregisteredagent.com/twist

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Today’s show: 

On today’s TWIST episode, Alex interviews two of the top startup co-founders: Keller Cliffton of Zipline and Anastasis Germanidis of Runway. 

Zipline announced its $600 million raise at a $7.6 BILLION valuation. Kellers breaks down the origins, economics, and future of Zipline’s contrarian bet in drone delivery. What was science fiction a decade ago is now a regular part of life for many. In fact, Zipline operates more flights than United!

Zipline is set to leapfrog the car delivery apps AND self driving cars with the superior economics of drone delivery. It is much cheaper to transport your burrito in a lightweight drone than a 6,000 pound self driving car!

Then, Alex is joined by Anastasis Germanidis, the CTO and co-founder of Runway, to explain why the next frontier of generative AI is world models! Runway  is looking to build a universal simulation, which will unlock massive gains in robotics, autonomy, and simulations. The world model would be able to simulate rare edge cases that could take years to find naturally! 

Check out how this cutting edge AI startup’s NYU Tisch School of Art’s origins

Then, See Jason’s answer to the question: “When should founders pivot or give up?”

Timestamps: 

(00:00) The Drone revolution is here!

(02:46) Inside Zipline’s factory to build 20K drones a year

(04:40) American dynamism Vs. Chinese manufacturing dominance

(09:00) How Zipline is growing 75% month on month

(9:50) Northwest Registered Agent. Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity —  Learn more at www.northwestregisteredagent.com/twist

(11:15) Zipline teleports food and goods to your house

(21:54) Crusoe Cloud: Crusoe is the AI factory company. Reliable infrastructure and expert support. Visit https://crusoe.ai/savings to reserve your capacity for the latest GPUs today.

(23:02) Is it affordable to use a drone to deliver a burrito?

(29:18) Zipline DOUBLES United’s flight numbers

(31:11) LinkedIn Jobs - post your job for free at http://linkedIn.com/twist then promote it to get access to LinkedIn Jobs new AI assistant.

(32:21) Anastasis break’s down Runway’s AI modeling

(35:24) Runway’s Gen 4.5 and the world model

(40:57) Why do robotics companies need a world model?

(43:04) Using AI to simulate robot laundry folding

(52:37) Runway’s origins at NYU’s art school

(55:46) Founder Q/A: When to pivot or give up on your startup

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Thank you to our partners:

(9:50) Northwest Registered Agent. Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity —  Learn more at www.northwestregisteredagent.com/twist

(21:54) Crusoe Cloud: Crusoe is the AI factory company. Reliable infrastructure and expert support. Visit https://crusoe.ai/savings to reserve your capacity for the latest GPUs today.

(31:11) LinkedIn Jobs - post your job for free at http://linkedIn.com/twist then promote it to get access to LinkedIn Jobs new AI assistant.

Check out all our partner offers: https://partners.launch.co/