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Scientific break-throughs are happening all around you. As technology advances, biologists such as the Chief Science Officer of the SENS Research Foundation, Aubrey de Grey, is leading the way to pioneering tech that will allow you to choose how long you want to live. For years scientists have been trying to find a way to slow down the aging process, but Aubrey introduces the idea of repairing the damage that aging does on the body to theoretically restore the body's biological age to maybe 30 years younger. If you are familiar with the obsession I've had with living forever, you already know how much this excites me.

SHOW NOTES:

Quality of Life | Aubrey on why a long life depends on the quality and being invested in choice [0:58]

Reverse Aging | Why damage repair could be easier than slowing aging & the push back met [4:40]

Indefinite Life | Aubrey on why the result of expected life for reversed aging could be indefinite [8:08]

Structure Repair | Landing on the idea of repairing structure to restore cellular level function [9:32]

Pushback | Aubrey on pushback among scientists about reverse aging in biology [11:17]

Body Damage | Aubrey on self-inflicted damage being reversed to same level 30 years prior [14:13]

Longevity Escape Velocity | Aubrey on his theory how to reverse biological age 30 years [16:26]

Types of Damage | 7 categories of damage that correspond to therapeutic methods of repair [21:18]

Stem Cell Therapy | Aubrey explains how stem cells could treat loss of cell problems [22:17]

Cancer Treatments | Aubrey gives category of damage due to too many cells [23:26]

Senescent Cells | Aubrey explains how these cells can promote cancer [26:53]

Mitochondrial Mutations | Aubrey explains problems at the molecular level inside cells [28:53]

Cellular Waste | Aubrey breaks down how cellular waste over years impacts old age [33:35]

Macular Degeneration | Aubrey explains specific enzymes that could prevent blindness  [35:24]

Excretion | Aubrey explains diseases that could be resolved by breaking down waste [37:50]

Alzheimer's | Breaking down amyloid as extracellular waste and modest benefit [39:22]

Advancing Therapies | Aubrey gives sobering guess how close effective therapies are [44:07]

QUOTES:

"I want to make sure that my choice about how long to live, and, of course, how high quality that life will be, is not progressively taken away from me by aging." [2:24]

"Old age is something that evolution doesn't care about at all. Evolution only cares about the propagation of genetic information." [34:41]

"you've got to fix them all. You haven't got to fix any of them perfectly. But you've got to fix them all pretty well." [43:28]

"what excites me is typically the breakthroughs that would take me half an hour background to describe why it's even important." [46:16]

Guest Bio:

Dr. de Grey is the biomedical gerontologist who devised the SENS platform and established SENS Research Foundation to implement it. He received his BA in Computer Science and Ph.D. in Biology from the University of Cambridge in 1985 and 2000, respectively. Dr. de Grey is Editor-in-Chief of Rejuvenation Research, is a Fellow of both the Gerontological Society of America and the American Aging Association

Follow Aubrey De Grey:

Website: https://www.sens.org/

Twitter: https://twitter.com/aubreydegrey

LinkedIn: https://www.linkedin.com/in/aubrey-de-grey-24260b/

Dive Deeper On Related Episodes:

Reset Your Age with David Sinclair https://youtu.be/IEz1P4i1P7s

Lifestyle For Longevity with Kellyann Petrucci https://youtu.be/l9QO0JlnU8w

Secrets To Longevity https://youtu.be/Ulm01gzU8rU

When someone points out your flaws and tries to put the blame on you for this or that, it's so easy to feel triggered. When it's your spouse, your partner, or someone you love that's doing it, it's even easier to get defensive and feel hurt. But what if your partner is also doing it in a way that makes them feel great and more amazing in comparison? Tom and Lisa walk through both sides of this scenario for how to cope with being criticized and blamed when you're being attacked and also feeling attacked. Over and over we come back to communication really being key to a healthy, happy, and long-lasting relationship. Today is no exception, let's talk about being defensive and the best way to think about it.

SHOW NOTES:

Feeling Attacked | Explore why you're feeling attacked and how to interpret the situation [0:40]

Being Attacked | Tom explains his response if he were being attacked [3:13]

Defensive | Lisa's advice for not feeling defensive when your intentions fail [5:11]

QUOTES:

"I never lead with this person is attacking me, I always lead with why am I feeling attacked?" Tom Bilyeu [2:25]

"If you get what you intended, you have done the right thing. If you do not get what you intended, [...] you have, by definition, used the wrong strategy." Tom Bilyeu [4:10]

"for whatever reason, using that word with me does rattle me, so use this word instead, so I can hear what you're saying." [6:35]

Famed biohacker and best-selling author Dave Asprey is used to being on the cutting edge of functional medicine. Now he is trying to help everyone become superhuman and live to 180 (or beyond). On this episode of Health Theory with Tom Bilyeu, Dave Asprey discusses the primary dietary mistakes people make, advocates for some pretty unusual health practices, and details simple, inexpensive changes you can make to reverse the aging process and radically improve your day-to-day health.

SHOW NOTES:

Dave talks about how to face death [1:14]

Tom and Dave discuss reincarnation [4:04]

Dave explains that the key is not time or money, but energy [6:41]

The first step to living to 180 is to not die [8:10]

Aging is death by a thousand cuts so the key is to take less cuts [11:07]

Aging boils down to the mitochondria [11:43]

Dave describes some tactics to optimize your mitochondria [14:49]

Dave explains his methods of fasting [17:05]

Dave describes chryotherapy, cold showers and cold exposure [22:10]

Dave and Tom discuss dietary and weight loss mistakes [26:13]

Dave discusses the utility of sometimes using a vegan diet [29:23]

Dave advocates not overdoing protein consumption [31:07]

Dave does not advocate a carnivore diet but suggests trying it for a brief time [34:36]

Dave gives some simple recommendations to become superhuman [38:14]

Dave talks about using amber light and red light [40:54]

Dave advocates better sleep as the single most important change people need to make [44:56]

FOLLOW DAVE:

WEBSITE: https://daveasprey.com

INSTAGRAM: https://bit.ly/2ECxRKg 

FACEBOOK: https://bit.ly/2SaYpKo 

TWITTER: https://bit.ly/2SaYgXm

How malleable are we? How much can we "supercharge" our brains? How much does diet affect the mind? Renowned neurosurgeon Rahul Jandial has spent his life tackling the toughest medical questions about the brain and the mind. On this episode of Health Theory with Tom Bilyeu, he shares his extraordinary knowledge about how much food affects our mindset, how to strengthen our brains, and what we can realistically expect from our efforts.

SHOW NOTES

Rahul discusses how brain injuries can sometimes uncover hidden potential [2:48]

Rahul explains how much brain training can really help [4:16]

Rahul gives specific tips on how to make the brain healthier [6:04]

Rahul explains the mind diet [10:41]

Rahul and Tom discuss how intermittent fasting kicks the mind diet into high gear [12:16]

Rahul talks about how even animals get high, and how plants work on your brain [18:20]

Rahul talks about measuring brain electricity [23:27]

Rahul and Tom discuss habits and brain plasticity [27:10]

Use it or lose it [31:14]

Rahul discusses mental health [34:16]

Rahul explains the complexity of depression and anxiety [38:49]

Rahul and Tom discuss how repetition creates positive mental habits [42:30]

Rahul explains the importance of physical exercise [45:08]

Rahul shares the one most important change people should make [48:21]

FOLLOW RAHUL

WEBSITE: http://bit.ly/2Y2ygkB

INSTAGRAM: http://bit.ly/32kHs2L

FACEBOOK: http://bit.ly/2LTm1QT

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You make think of insulin resistance as being reserved for diabetics, and you may have even drawn the same conclusion I have, that the problem is glucose being too high. After speaking with Ben Bikman, a scientist that studies metabolic disorders caused by insulin resistance, I was shocked to find out that insulin resistance can still develop even in people with seemingly normal glucose levels. Ben's explanation of the complicated nature of insulin in the body and his unique take on facts that can literally save your life with knowledge are exactly what we need more of.  Whether you consider yourself to be healthy, prediabetic, or struggling with other health issues this episode may give you the insight you need today.

Order Dr. Benjamin Bikman's new book, Why We Get Sick: https://www.amazon.com/Why-We-Get-Sick-Disease_and/dp/194883698X

SHOW NOTES:

Glucose | Ben on why leaving insulin levels unchecked to check glucose is problematic [1:07]

Hyperglycemia | Ben reveals the dangers of elevated sugar levels in the body [6:06]

Nerve & Vascular Damage | Ben explains how hyperglycemia destroys these systems [8:34]

Glucose Control | Ben on the simple solution to eat less sugar vs. prescription choices [11:58]

Diet Habits | Changing dietary habits to control glucose vs medication and power of diet [15:10]

Insulin Resistance | Ben explains 2 problems, cells not responding and elevated insulin [18:47]

Storing Fat | Ben maps out which cells are resistant to insulin & which will store more fat [23:50]

Elevated Insulin | Ben explains the effect of insulin and how too much affects your cells [31:40]

Hypertension | Ben reveals how insulin is nearly always tied to high blood pressure [32:23]

Exercise Cure | Ben on how exercise impacts insulin levels and muscle cells take over [36:37]

Diet | Ben underlines that diet beats exercise in terms of helping insulin resistance [41:38]

Diet Principle #1 | Control Carbs, Ben explains why carbs are not essential for humans [42:31]

Vegan Diet Problems | Ben explains how vegan diets are missing iron and omega 3s [44:26]

Diet Principle #2| Prioritize Proteins, Ben urges animal-sourced proteins are best [47:17]

Diet Principle #4 | Fasting, Ben simplifies it and only advises eating earlier is better [50:01]

QUOTES:

"when you start asking someone to change habits, you are probably asking them to do the most difficult thing they can do. It's just so much simpler to take a pill. And consequences be damned" [15:31]

"... it might be empowering, that rather than hopelessly taking medications every day, knowing that the only the only future is increasing the dose of those medications. Let's actually address the true origins of the problem, which [...] is often going to be insulin resistance." [18:17]

"insulin's telling the body how much fat to store, the sex hormones are just telling the body where to store it, and how" [28:08]

"the muscle is so hungry during exercise, that it just basically tells insulin look when I'm at rest, you're the boss, but when I'm exercising, I'm the boss. I'm going to get what I need, and so it basically pushes insulin to the side." [39:01]

"if you try to compare diet to exercise, diet will beat the hell out of exercise, as a variable for insulin resistance." [42:00]

"it [vegan diet] is a privilege of the elite. You have to be educated enough to know what your deficiencies are, and you have to be wealthy enough to afford the supplements" [44:47]

Follow Ben Bikman:

Website: https://www.insuliniq.com/about-dr-benjamin-bikman

Twitter: https://twitter.com/benbikmanphd?lang=en

Facebook: https://www.facebook.com/insuliniq

Instagram: https://www.instagram.com/benbikmanphd/?hl=en

Youtube: https://www.youtube.com/channel/UCblbxPFG0XAsQA2LwzT6xDQ

This weeks guest on Health Theory is Harpreet Rai.  Harpreet is an entrepreneur and the CEO of Oura Ring.  In this episode he talks about how to improve your sleep through tracking, how sleep improves your focus and his tips for losing weight.

SHOW NOTES

Why sleep matters [01:21]

The importance of sleep for your overall health [02:09]

What happens when we don't sleep enough [06:15]

How to balance your work life with getting enough sleep [08:08]

How our sleep is disrupted [11:28]

What happens during each phase of sleep [14:32]

Lifestyle tips to improve your sleep [18:10]

How to use sleep tracking to determine the best workout for you each day [24:16]

The importance of deep sleep [27:04]

How diet changes your sleep quality [29:12]

Why you want high heart rate variability [30:36]

Can meditation improve your heart rate variability? [32:59]

The reason it's hard to track naps [35:44]

The future of wearables and data tracking [37:23]

What health markers people should track [43:58]

The best exercise for sleep [47:23]

How athletes use sleep and hyperbaric chambers to improve recover [49:04]

FOLLOW HARPREET:

WEBSITE: https://bit.ly/1TqiRON

INSTAGRAM: https://bit.ly/2OvqF9a

FACEBOOK: https://bit.ly/2NiMPXE

Mark Sisson is a former endurance athlete turned nutrition author and entrepreneur. In 2006, he began his popular health blog, Mark's Daily Apple, where he's blogged every day for 12+ years. Mark is the founder of Primal Kitchen Foods and best-selling author of several books including The Primal Blueprint and his most recent hit, The Keto Reset Diet.

Health Theory is a bi-weekly interview show, hosted by Quest Nutrition co-founder, Tom Bilyeu. Each episode offers tactical steps one can take to improve their wellbeing and achieve their goals.

SHOW NOTES:

What does primal really mean? [02:19]

The importance of dietary fat [05:20]

The context of calories [08:08]

What is metabolic flexibility [09:42]

Endurance training using old technology [12:18]

Ketogenics and endurance training [16:44]

Does keto allow you to eat less? [19:35]

Reframing how you think about sacrifice [23:34]

The Keto Reset Diet [29:50]

Finding your food limits [34:35]

How eliminating grains cured Mark's IBS [38:46]

Why keto may improve your microbiome [43:37]

Living awesome [47:25]

MENTIONED IN THIS EPISODE:

Primal Endurance: http://amzn.to/2F1X0fJ

The Primal Blueprint: http://amzn.to/2BUGZtr

The Keto Reset Diet: http://amzn.to/2BVdoA2

Mark's Daily Apple: http://bit.ly/2F9tyYB

Primal Kitchen Foods: http://bit.ly/2p0qB5S

The Context of Calories: http://bit.ly/2oALkK1

Phinney & Volek: http://bit.ly/2hZW6F5

FOLLOW MARK SISSON:

FACEBOOK: http://bit.ly/20XnWRj

INSTAGRAM: http://bit.ly/2CNhNli

Dr. Caroline Leaf is a powerhouse researcher dedicated to unlocking the human mind's untapped potential. And that potential looks to be almost limitless. On this episode of Health Theory with Tom Bilyeu, Caroline Leaf explains the biological processes that constitute thoughts, feelings and choices, emphasizes the importance of becoming more aware, and describes the latest brain research, including exciting findings about how to change your biological age through mind management.

You can pre-order Dr. Leaf's new book here: https://amzn.to/3fbM9kX

SHOW NOTES:

[00:00] Form Your Identity: Caroline explains why your identity is so important, and how to consolidate and strengthen it.

[06:48] Think, Feel, Choose: Caroline describes the biological processes that underlie making choices and building identity.

[14:43] The Science of Thought: Caroline uses the analogy of ocean waves to explain how the brain functions.

[23:43] How to Become Aware: Awareness is strongly linked to empathy, and requires you to stand back and observe your own choices and reactions.

[28:45] 5 Steps for Mind Management: Even if you are not conscious of it, and even if you don't remember it, your choices and habits will change your brain on a physical level.

[44:03] The Latest Researcher: You can change your biological age by controlling your brain functions.

Follow Dr. Leaf:

WEBSITE: https://drleaf.com

INSTAGRAM: https://instagram.com/drcarolineleaf/

FACEBOOK: https://facebook.com/drleaf/

TWITTER: https://twitter.com/DrCarolineLeaf

APP: https://theswitch.app

DR. LEAF'S PODCAST: https://anchor.fm/cleaningupthementalmess

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Which diet are you following? Are you doing the carnivore diet? Vegan? Keto? The choices and variations of every diet plan available is nearly endless. At the heart of the matter, diet consciousness is a question of overall health and better managing and preventing diseases and conditions that hinder your performance and destroy your ability to live a happy and healthy life. In this episode, nephrologist and intermittent fasting expert, Dr. Jason Fung, exposes the overarching importance of understanding your body's hormonal response to insulin activated by what you eat and the frequency with which you eat. He also breaks down the three major paradigms for cancer, and ranks the danger of a poor diet as high as cigarette smoke in terms of high risk contributors of cancer. Dr. Fung is also the author of the #1 best seller, The Obesity Code.

Order Dr. Jason Fung's Book, "The Cancer Code": https://www.amazon.com/Cancer-Code-Revolutionary-Understanding-Wellness/dp/0062894005

SHOW NOTES:

Weight Loss | Dr. Fung on why weight loss is critical and counting calories doesn't work [1:23]

Calories | Dr. Fung reveals how hormones impact your body's response to less calories [3:31]

Carbohydrates | Dr. Fung on how carbs stimulate insulin and signal the body to store fat [6:59]

Protein vs. Carbs | The hormonal response of these nutrients on satiety & effect on insulin [9:50]

Processed Carbs | Dr. Fung explains the danger behind processed carbs & hormones [13:03]

Insulin | Dr. Fung explains getting fat on calorie restriction when insulin is high [15:49]

Low Insulin Diet | Dr Fung on losing weight by lower insulin and cycle feeding & fasting [23:32]

Fasting | Dr. Fung introduces options to get through fast with salt, magnesium or broths [26:32]

Cancer | Dr. Fung breaks down 3 paradigm shifts in cancer research & treatments [28:50]

Growth Paradigm | How the overgrowth of cells have been treated by cut, burn or poison [29:41]

Genetic Paradigm | Understanding genetic mutations and the complication curing cancer [30:36]

Evolutionary Paradigm | The primitive mutation of cancer treated with immunotherapy [34:00]

Seed in Soil | Preventing cancer "seeds" to grow, understanding chronic stressors  [42:30]

QUOTES:

"So it's simply false to say, if you cut 500 calories a day down, you will lose a pound of body fat a week, it's actually not true in any way, shape, or form." [5:31]

"when you're thinking about weight gain, weight loss, you really have to think about hormones, because it's really a hormonal imbalance, not a caloric imbalance" [12:04]

"when insulin is going down you're going to burn body fat, [...] you can't burn body fat if insulin is high." [21:05]

"...we're not trying to kill cells with immunotherapy, we're not trying to fix genetic mutations. What we're trying to do is treat these cancers like a foreign species, like an invasive foreign species..." [40:03]

"diet actually plays a massive role, and by understanding it, perhaps you can reduce your risk of cancer." [47:45]

Follow Dr. Jason Fung:

Website: https://thefastingmethod.com/

Facebook: https://www.facebook.com/jason.fung.313

Instagram: https://www.instagram.com/drjasonfung/

Twitter: https://twitter.com/drjasonfung

Youtube: https://www.youtube.com/channel/UCoyL4iGArWn5Hu0V_sAhK2w

Functional Medicine Practitioner and author of How to Make Disease Disappear, Rangan Chatterjee, joins Tom on this week's episode of Health Theory. Dr. Chatterjee explains his four pillars of health and why balance across the four, rather than perfection in one, is essential. 

Why most disease can end through lifestyle change [0:37]

Why is life expectancy going down? [2:01]

What is epigenetics and why is it exciting? [4:50]

Keeping health simple [6:45]

Lifestyle over diet and the 'threshold' concept [7:26]

A 360 degree approach to improving health  [10:06]

Why we shouldn't completely demonize carbs [14:44]

Why strength training is undervalued [18:18]

A simple fix to widely common mistakes [20:30]

The psychology behind food choices [23:38]

Why mindful eating matters [28:04]

Short-term pleasure vs. long-term consequences [29:30]

Why when we eat is just important as what we eat [30:53]

Prioritizing and enhancing sleep quality [33:24]

The importance of 'me' time [35:45]

The value of root-case medicine [37:05]

DISCUSSED IN THIS EPISODE

How To Make Disease Disappear by Rangan Chatterjee: https://amzn.to/2tkHQOh

BBC Show "Doctor In The House": https://youtu.be/j9HPSP7QwPU

FOLLOW RANGAN CHATTERJEE

WEBSITE: https://bit.ly/2M4D7In

PODCAST: https://bit.ly/2ljsOVn

FACEBOOK: https://bit.ly/1U9TRtW

INSTAGRAM: https://bit.ly/2JMcT0d