In this episode Dr. Gillian Beauchamp sits down with Dr. Robert "Cole" Pueringer to discuss 3 key features of fentanyl which lead to high opioid tolerance. This high opioid tolerance can lead to more severe withdrawal syndromes and difficulty with initiating buprenorphine or methadone. Rapid inpatient methadone initiation may be more effective than outpatient initiation.

In this episode Dr. Gillian Beauchamp sits down with Dr. Benjamin Hatten to discuss the potential role of psychedelics in palliative care medicine. Specifically data that shows improved outcomes in individuals who experience psychological stress related to a terminal or life limiting illness that is refractory to more traditional treatments such as antidepressants

In this episode Dr. Gillian Beauchamp sits down with Dr. Patil Armenian to discuss strategies to promote physiologic as well as well as mental/emotional/psychiatric safety when psychedelics are used therapeutically and recreationally.

In this episode Dr. Gillian Beauchamp sits down with Dr. Laurie Halmo discuss the challenges of making informed recommendations in regard to use of substances during pregnancy.

In this episode Dr. Gillian Beauchamp sits down with Dr. John Downs to discuss recommendations for at risk occupational PFAS testing (Aviation fire fighters, certain agricultural workers (exposure to " bio sludge" , workers exposed to organofluorines, ski waxers) and challenges of generalized testing.

In this episode Dr. Gillian Beauchamp sits down with Dr. Albert Garcia Romeu to discuss the history of psychedelic use, current treatment protocols and research on using psychedelics to support recovery from substance use disorders.

In this episode Dr. Gillian Beauchamp sits down with Dr. Michael Twiner and Dr. Brett Johnson to discuss harmful algal blooms (HABs) such as inhalation toxicity from Red Tide, neurotoxic shellfish toxicity, diarrheal shellfish poisoning, and amnestic shellfish toxicity.

In this episode Dr. Gillian Beauchamp sits down with Dr. Michael Toce to discuss naloxone access laws, increased community availability of naloxone and who still doesn't have access to naloxone. They also discuss the difference between naloxone and nalmefene and the future of nalmefene.

In this episode Dr. Gillian Beauchamp sits down with Dr. Kevin Wenzel, PhD to discuss the importance of family involvement including identifying substance use disorder, seeking treatment and providing support during treatment.

In this episode Dr. Gillian Beauchamp sits down with Jonathan Jarry MSc to discuss trends in health related pseudoscience and our role in fighting misinformation.