ToxNow

ToxNow

By ToxNowMedicine
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ToxNow episodes

  • Episode 25 Lipid Rescue Part 2

    In this episode we have the second half of our interview with Guy Weinburg and Michael Fettiplace about developments in lipid rescue, more than just a “lipid sink”. Contributors include Matthew Zuckeman, Michael Fettiplace, and Guy Weinburg. More info at LipidRescue.org

    The post Episode 25 Lipid Rescue Part 2 first appeared on ToxNow.

    46 min
  • Episode 24 Lipid Rescue Part 1

    In this episode we have the first half of our interview with Guy Weinberg where we talk about the history and development of lipid rescue. Contributors include Matthew Zuckerman and Guy Weinberg. More info at LipidRescue.org

     

    Articles featured

    • Weinberg GL, VadeBoncouer T, Ramaraju GA, Garcia-Amaro MF, Cwik MJ. Pretreatment or resuscitation with a lipid infusion shifts the dose-response to bupivacaine-induced asystole in rats. Anesthesiology. 1998 Apr;88(4):1071-5.
    • Rosenblatt MA, Abel M, Fischer GW, Itzkovich CJ, Eisenkraft JB. Successful use of a 20% lipid emulsion to resuscitate a patient after a presumed
    • bupivacaine-related cardiac arrest. Anesthesiology. 2006 Jul;105(1):217-8.
    • Sirianni AJ, Osterhoudt KC, Calello DP, Muller AA, Waterhouse MR, Goodkin MB, Weinberg GL, Henretig FM. Use of lipid emulsion in the resuscitation of a patient
    • with prolonged cardiovascular collapse after overdose of bupropion and lamotrigine. Ann Emerg Med. 2008 Apr;51(4):412-5.
    • Fettiplace MR, Lis K, Ripper R, Kowal K, Pichurko A, Vitello D, Rubinstein I, Schwartz D, Akpa BS, Weinberg G. Multi-modal contributions to detoxification of
    • acute pharmacotoxicity by a triglyceride micro-emulsion. J Control Release. 2015  Jan 28;198:62-70.

      The post Episode 24 Lipid Rescue Part 1 first appeared on ToxNow.

      23 min
    • Episode 23 Mushroom Poisoning

      In this episode we talk about the spectrum of mushroom poisoning from Amanita to magic mushrooms. Contributors include Matthew Zuckerman and the UMass Toxicology team Kavita Babu, Katie Boyle, Lynn Farrugia, Stephanie Carreiro, Peter Chai, and Viral Patel along with Mark Neavyn. Mushroom pictures are available here.

      The post Episode 23 Mushroom Poisoning first appeared on ToxNow.

      51 min
    • Episode 22 Not That Kind of Mustard

      In this episode we talk to Dr. Kathryn Weibrecht about a US case of mustard exposure and how to identify and treat these cases. MMWR case series can be found here and a link to the case in Annals can be found here. Contributors include Matthew Zuckerman and Kat Weibrecht.

      The post Episode 22 Not That Kind of Mustard first appeared on ToxNow.

      22 min
    • Episode 21 Here Today, Gone Tomorrow?

      In this episode we talk to Dr. Leo Schep from the National Poisons Centre of New Zealand about the country’s experience with regulating synthetic cannabinoids, known there as “Legal Highs”. Afterwards, you’ll get a first peek at the new talking naloxone autoinjector. Contributors include Matthew Zuckerman and Leo Schep from University of Otago. More information about NZ regulation of legal highs can be found here.

      The post Episode 21 Here Today, Gone Tomorrow? first appeared on ToxNow.

      41 min
    • Episode 20 Acetyl Fentanyl and CDC

      In this episode we talk to Katherine Kimbrell, an EM doc in RI, as well as Matt Lozier and Molly Boyd from CDC about the emerging acetyl fentanyl deaths and their investigation

      The post Episode 20 Acetyl Fentanyl and CDC first appeared on ToxNow.

      43 min
    • Episode 19 Suicide Gas

      In this episode we talk about a mystery gas increasingly used in suicides and get a first hand account from Nick Connors from the NYCPCC.  Articles mentioned are available here and a link to the Frontline documentary. Contributors include Nick Connors and Matt Zuckerman.

      The post Episode 19 Suicide Gas first appeared on ToxNow.

      24 min
    • Episode 18 Medical Child Abuse Conference

      For this episode we recorded a joint conference with the Aubin Child Protection Center at Hasbro Children’s Hospital. The team discusses evaluating a child for medical child abuse and the unique challenge of interpreting lab results.

      The post Episode 18 Medical Child Abuse Conference first appeared on ToxNow.

      1 hr 6 min
    • Episode 17 Krokodil Kraze

      In this episode, we talk to Maximilian Gahr about the US emergence of desomorphine (Krokodil) and implications for investigation and treatment. Reports coming out of Arizona and Illinois, are reminiscent of past reports from Germany. Dr. Gahr’s articles on Krokodil can be found here. Contributors include Matthew Zuckerman and Maximilian Gahr.

      The post Episode 17 Krokodil Kraze first appeared on ToxNow.

      23 min
    • Episode 16 Sarin in Syria

      In this special episode we follow up with Steve Bird to talk about what kinds of confirmatory tests are going on to determine if Sarin was used in Syria. This is a follow up to Episode 7 where we talked about the toxicology of organophosphates and nerve agents. Contributors include Matt Zuckerman and Steve Bird.

      The post Episode 16 Sarin in Syria first appeared on ToxNow.

      22 min

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