By Prof Nick James and Dr Hoda Aty
The podcast currently has 10 episodes available.
In this episode, Mr Ashwin Sachdeva, Consultant Urologist and Academic Clinical Lecturer at the University of Manchester discusses the following:
00:00 Introduction
02:10 Utilising NHS Data for long-term follow-up
04:40 Fracture rates and hormone therapy in prostate cancer
07:05 Challenges in trial follow-up and data collection
11:18 Imaging and its role in prostate cancer
17:58 Prospective imaging collection in the STAMPEDE trial
22:32 Balancing surgery and research
26:31 Future directions in prostate cancer research
In this episode, Professor Michael Hofman shares his experience with PSMA theranostics trials in prostate cancer, particularly focusing on the ProPSMA and TheraP trials.
He emphasises the advancements in PSMA PET imaging, highlighting its prognostic and predictive significance, as well as the importance of accurate imaging in guiding treatment decisions.
He also addresses the challenges of conducting imaging clinical trials and discusses the importance of industry collaboration in research.
In Episode 8, featuring Professor Udai Banerji, we discuss the set up of early phase clinical trials.
In Episode 7, featuring Professor Neha Vapiwala, we discuss the strengths and challenges of clinical trial setup in the US, the intricacies of international collaborations, and provide an overview of next-generation imaging with PSMA PET in the STAMPEDE2 and INDICATE clinical trials.
In episode 6, featuring Professor Piet Ost, we explore what works well and the challenges with international clinical trial collaborations.
In episode 5, featuring Professor Silke Gillessen and Professor Vedang Murthy, we explore what works well and the challenges with international clinical trial collaborations.
Timestamps:
(00:00)- Introduction
(00:28) - Silke Gillessen
(05:02) - Interlude
(05:05) - Vedang Murphy
In Episode 4, featuring Professor Silke Gillessen, we explore the STAMPEDE trial’s Metformin comparison, discussing its rationale and predicted outcomes. We also tap into challenges with access to routine data and clinical trial regulation.
In episode 3, we discuss the set-up of the STAMPEDE2 trial database and the first site initiation visit (SIV). We also give an overview of the STAMPEDE2 trial design.
In episode 2, we discuss the challenges that clinical trials face in accessing routinely collected data.
In episode 1, we discuss the STAMPEDE2 trial site set-up, ethics and MHRA issues.
The podcast currently has 10 episodes available.