Medical missions are often challenging because of cross-cultural exposure to unfamiliar diseases in settings with limited diagnostic resources. Common tropical illnesses are generally unfamiliar to US trained providers. This session will present real cases from Africa and Asia focusing on tropical skin diseases, HIV, diarrhea, fever and malnutrition. History and visual clues along with simple lab and x-rays will guide our discussions and help you be better prepared. Cases will be of interest to those with medical training or those serving in an area without easy access to medical care. Come and enjoy the game.