tv.qiagenbioinformatics.com

tv.qiagenbioinformatics.com

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tv.qiagenbioinformatics.com episodes

  • QIAGEN IPA new user training

    Are you new to QIAGEN Ingenuity Pathway Analysis (IPA) or interested in expanding your skill set? Join us as we learn more on large dataset analysis and knowledge base queries using QIAGEN IPA.

     

    You'll learn to:

     

    • Upload multiple dataset types (e.g., RNA-seq, proteomics, metabolomics) and perform interactive core/pathway analysis in IPA

    • Learn how to interpret different results, including pathways, key regulators, impact on biological functions/diseases and more

    • Compare different experimental conditions (e.g., single-cell clusters, disease types) and identify similarities and contrasts

    • Generate a network for hypothesis generation, even without a dataset or experimental design

     

    Already have an IPA license? Install IPA and start using it now: https://qiagen.showpad.com/share/CBv30blCPKFDUYHRWtAvI

     

    Learn more about IPA or request a free trial: https://digitalinsights.qiagen.com/products-overview/discovery-insights-portfolio/analysis-and-visualization/qiagen-ipa/

    1 hr 52 min
  • Public single-cell expression data made easy with QIAGEN IPA

    Many QIAGEN Ingenuity Pathway Analysis (IPA) users have expressed strong interest in taking advantage of public single-cell expression data. Such data is readily available and easily accessible in IPA. We are hosting a 1hr training focused on some common use cases related to this topic.

    You'll learn to:

    • Easily locate single-cell studies, samples or cell types of interest

    • Study pathways and networks pertaining to such projects to explore biological and cellular mechanisms
    • Investigate sample- and cell-level gene expression for biomarker investigation

    54 min
  • IPA deep dive miRNA investigation using QIAGEN Ingenuity Pathway Analysis

    In this 90-minute training session, you will learn how to identify target mRNAs for your miRNAs of interest and associate them with pathways, diseases, biological functions, tissues and cell types.

    Topics that will be covered include:

    • How to analyze miRNA-seq datasets alone or both miRNA and corresponding mRNA datasets together

    • How to use QIAGEN IPA without a dataset, using miRNA IDs
    • Introduction to databases and curated content specific to miRNA
    • How to effectively apply various filters and functionalities to identify biomarkers, key targets and biological mechanisms

    1 hr 24 min
  • Link prediction for biomedical innovation and drug discovery

    Are you interested in biomedical knowledge graphs, but don’t know where to start? This webinar will show you how to repurpose drugs and uncover hidden insights with knowledge graphs. Start learning the fundamentals of training embeddings and how to predict links in knowledge graphs. You’ll be able to apply that knowledge towards your biomedical discoveries with advanced machine learning techniques.

    In this webinar, you will:

    • Meet QIAGEN Biomedical KB-HD, the manually curated knowledge base of over 24 million relationships that powers QIAGEN Ingenuity Pathway Analysis

    • Learn about methods for graph link prediction
    • Start applying link prediction to graph embeddings with PyKEEN
    • See the results of applying link prediction towards indication expansion for a TLR7 inhibitor

    1 hr 3 min
  • OmicSoft Studio RNA-seq and expression data analysis

    In this 90-minute training, attendees will learn how to use basic expression analysis (example RNA-seq) functionalities in QIAGEN OmicSoft studio and how that integrates with OncoLand, DiseaseLand and Single Cell Land. This webinar will focus on expression data analysis using QIAGEN OmicSoft Studio’s powerful analysis and visualization capabilities to explore your ‘omics data: 


    • Accepted data formats (ex. fastq files, cell matrix files with raw or normalized counts, etc.)  
    • Easily generating and flexibly customizing downstream outputs such as differential expression, heatmaps, counts, PCA/PCOA, etc. 
    • Exporting high-resolution graphics as well as raw or filtered tables

    To make most out of this training, please consider reviewing below ahead of time (not a requirement to attend the training though).

    Step-by-step local analysis: https://qiagen.showpad.com/share/4RlqPuRL3NbookmCybga2
    Step-by-step server analysis: https://qiagen.showpad.com/share/xCnBr2LPphZOyNihxORqn

    1 hr 29 min
  • Single-cell RNA-seq, cell hashing, and spatial transcriptomics

    A slide illustrating some of the many result types/graphics you will be able to generate after this training. https://qiagen.showpad.com/share/jYTCDPNfz1SdIMPQPSPYS

    Analyze and interpret your own single-cell RNA-seq data using QIAGEN CLC Genomics Workbench, starting with either FASTQ or matrix files.

    Learn how to perform the different steps of secondary analysis on your single-cell RNA-seq data, such as:

    • Importing your raw FASTQ or processed cell-matrix files

    • Using preconfigured but customizable pipelines/workflows for single-cell RNA-seq data.
    • Generating high-resolution visuals and other files from your analysis, for publications and biopharmaceutical discoveries.
    o Dimension reduction (UMAP, t-SNE) plots
    o Differential expression tables for clusters, cell types or a combination of both
    o Heat maps o Dot plots o Violin plots
    • Using the “Create Cell Annotations from Hashtags” tool for cell hashing (e.g., CITE-seq).
    • Applying spatial transcriptomic analysis, the latest feature in the single-cell RNA-seq module

    1 hr 58 min
  • QIAGEN Ingenuity Pathway Analysis (IPA) for grant writing and publications

    IPA is more than just an analysis program; it can also help you write grants and publications. IPA provides biological insights backed by expert-curated findings and thousands of pre-analyzed multi-omics datasets. You can search for existing knowledge on molecules of interest, build networks and review results from public studies. Or you can identify key pathways, regulatory molecules and functional changes in your results and see how your data relates to published studies.




    You'll learn how to:
    • Search IPA’s vast collection of curated literature and omics data
    • Relate molecules to phenotypes and functions
    • Build your own networks and predict activity changes
    • Explore a library of over 90,000 precomputed IPA analyses pulled from publicly available studies
    • Format your dataset and set up an analysis
    • Deeply interrogate key Canonical Pathways
    • Predict regulators causing your observed expression changes
    • Contextualize your results by comparing them to internal and public data
    • Generate the necessary tables and figures for your manuscript

    2 hr 1 min
  • Leveraging the QIAGEN Knowledge Graph and causal embeddings for insights into...

    By connecting diverse entities and relationships, biomedical knowledge graphs hold the potential to uncover new insights from existing data. This webinar introduces a machine learning-based approach that utilizes causal interactions from the QIAGEN Knowledge Graph to predict novel drug-disease relationships and construct networks that capture relevant supporting evidence. We will present examples that showcase the application of this approach in the context of drug repurposing.

    59 min

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