Jessamy Bagenal and Kimberly Smith discuss implications arising from the Gemini study, which shows how a two-drug combination is not inferior to a conventional three-drug regimen in the treatment of HIV.

Two-drug regimen for HIV

The Lancet (www.thelancet.com) is a weekly medical journal, renowned for the publication of high-quality peer-reviewed research and reviews from around the world. In the Podcasts our editors discuss journal highlights, including interviews with authors of key articles to provide context and insight to advancements in medicine and health worldwide.

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Inappropriate use of opioids after surgery has contributed substantially to the global opioid epidemic. Lead author Paul Myles (Alfred Hospital and Monash University, Melbourne, Australia) discusses a new Lancet Series that proposes alternative approaches for pain management after surgery.

Postoperative pain management and opioids

TH Lam (University of Hong Kong) discusses a proposal for an international framework convention for alcohol control, given the totality of recent evidence that there is no safe limit for alcohol consumption.

A framework convention for alcohol control?

Shakila Thangaratinam (Queen Mary University of London, UK) discusses a systematic review and meta-analysis which highlights the increased risk of perinatal trauma and mortality associated with C-section use in low income and middle income countries.

c-Section in LMICs

A new Lancet Commission maps out priorities in diagnosis, treatment, prevention, and advocacy efforts to end tuberculosis by 2030. Detailed discussion with two of the commissioners: UN Tuberculosis Special Envoy Eric Goosby, and Paula Fujiwara from the International Union against tuberculosis and lung disease. The podcast is introduced by Liz Zuccala from The Lancet.

Building a tuberculosis-free world

Alan Stein, Brenda Kelly (University of Oxford, UK), and Ruth Bland (Royal Hospital for Children, Glasgow, UK) discuss a two-part Series that is helping to develop guidelines for health-care professionals and families concerning life-threatening conditions in children or their parents.

Two-drug regimen for HIV

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