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Tylenol, Glutathione & Pregnancy: Precaution Without Panic with guest Dori
We are breaking down what's up today with these new headlines hitting the news.
Studies to check out:
ACOG: “Acetaminophen in Pregnancy” FAQ + Sept 2025 statement reaffirming safety benefits when indicated. ACOG+1
Nature Reviews Endocrinology (2021) consensus: calls for precautionary action (minimize, lowest effective dose, shortest duration). Nature+1
Placental transfer/biotransformation: AJOG 2012 (rapid passage); 2019/2025 reviews on fetal exposure & CYP2E1 expression. AJOG+1
Mechanism reviews: Hinson 2010; Yan 2018; Liao 2023—NAPQI, GSH depletion, mitochondrial/JNK pathway. PMC+2PMC+2
Neurodevelopment associations: JAMA Psychiatry 2020 (cord biomarkers); JAMA Pediatrics 2020 (meconium + connectivity); cohort syntheses 2024–25 (mixed findings). PubMed+2JAMA Network+2
Male reproductive endpoints: Sci Transl Med 2015 (fetal testosterone ↓); human AGD/cryptorchidism studies & mixed evidence reviews. PMC+2PMC+2
Join the Adrenal and Stress Workshop Here
Get the Liver Rescue Workshop here --> https://super-sound-75917.myflodesk.com/liverreplay
Get the Parasites and Candida Workshop here
Disclaimer: This podcast is educational only and not medical advice. Decisions about medications in pregnancy should be made with your healthcare provider.
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By Hannah GreigWe are breaking down what's up today with these new headlines hitting the news.
Studies to check out:
ACOG: “Acetaminophen in Pregnancy” FAQ + Sept 2025 statement reaffirming safety benefits when indicated. ACOG+1
Nature Reviews Endocrinology (2021) consensus: calls for precautionary action (minimize, lowest effective dose, shortest duration). Nature+1
Placental transfer/biotransformation: AJOG 2012 (rapid passage); 2019/2025 reviews on fetal exposure & CYP2E1 expression. AJOG+1
Mechanism reviews: Hinson 2010; Yan 2018; Liao 2023—NAPQI, GSH depletion, mitochondrial/JNK pathway. PMC+2PMC+2
Neurodevelopment associations: JAMA Psychiatry 2020 (cord biomarkers); JAMA Pediatrics 2020 (meconium + connectivity); cohort syntheses 2024–25 (mixed findings). PubMed+2JAMA Network+2
Male reproductive endpoints: Sci Transl Med 2015 (fetal testosterone ↓); human AGD/cryptorchidism studies & mixed evidence reviews. PMC+2PMC+2
Join the Adrenal and Stress Workshop Here
Get the Liver Rescue Workshop here --> https://super-sound-75917.myflodesk.com/liverreplay
Get the Parasites and Candida Workshop here
Disclaimer: This podcast is educational only and not medical advice. Decisions about medications in pregnancy should be made with your healthcare provider.