UC San Diego (Audio)

This presentation will briefly trace 70,000 years of cultural evolution from the ancient crossing from Sunda to Sahul, via the swift continental colonization during the Ice Age, through the severe impacts on survival during the Last Glacial Maximum, and the socio-territorial reconfigurations during Holocene sea-level rise. The Australian Aboriginal world had become characterized by low environmental impact habitation, complex social organization systems anchored within constructed sacred origin histories, the persistence of relatively simple dwelling types situated within complex settlement sociospatial structures, and a high quality of life for most, with institutional dispute resolution mechanisms to contain conflicts. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40162]

Catriona Jamieson, M.D., Ph.D., discusses pioneering research on cancer and aging in space environments, highlighting how microgravity accelerates cancer cell growth and leads to stem cell exhaustion, genomic instability, and “dark genome” activation. Using innovative tools like nano-bioreactors and artificial intelligence, her team simulates these effects and tracks cellular changes, uncovering how space’s unique conditions drive mutations and alter cellular behavior. They find that stem cells rapidly proliferate but then become exhausted in space, a process tied to telomere shortening and mitochondrial stress, impacting cell longevity and regenerative potential. Through collaborations with NASA and industry partners, Jamieson’s research aims to develop therapies to counter these effects, offering potential insights for cancer treatment and stem cell health on Earth. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39948]

A glimpse of gospel, jazz, and soul from the great legends is what inspires the sound of pianist Theron Brown’s music. But the reason he plays is to encourage and influence people through his talents. Originally from Zanesville, Ohio, Theron currently resides in Akron, Ohio, where he is Professor of Practice at The University of Akron teaching jazz piano, and the program coordinator for Curated Storefront’s Artist Residency Program at the ‘I Promise School’. Theron also serves as an educator for the interactive piano learning app, Playground Sessions. He is heavily involved in the music community as the founder and artistic director of the Rubber City Jazz & Blues Festival, which takes place annually in Akron, Ohio’s downtown historic district. Theron performs and tours regularly with his trio that includes Zaire Darden on drums and Jordan McBride on bass. He is currently working on his second album. Series: "Arts Channel " [Arts and Music] [Show ID: 40023]

The transition from Neolithic villages to early cities marked the greatest social transformation faced by our species before the Industrial Revolution. Our ancestors had to learn how to live in new settlements that had more people, higher densities, and more activities than had been known previously. The new adaptations to urban life involved changes in society and social processes, not just individual learning. Some changes came about through social interactions in a process called energized crowding; these include innovations in housing and the use of space, and the establishment of neighborhoods in cities. Other changes were driven by powerful new institutions, including formal governments and social classes. Do ancient cities—and they ways they responded to shocks—might hold useful insights for the development of urban adaptations to climate change today? Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40165]

Through the UniversityLink Medical Science Program (ULMSP), college students from underrepresented and disadvantaged backgrounds who aspire to become future health science professionals develop essential academic and professional skills, benefit from long-term mentoring, and build lasting social and professional networks. Dr. Ramón A. Hernandez highlights how the program fosters family support, instills a culture of academic excellence, and emphasizes the importance of community service, showing how ULMSP helps pave the way for these students' success in the health sciences. Series: "Education Channel" [Health and Medicine] [Education] [Show ID: 37921]

Humans construct their physical worlds in part by designing and constructing new tools, habitations, and in due course diverse buildings and, in some cases, towns and cities and construct their symbolic worlds by putting words together to tell stories, articulate plans, tell lies, seek truth, and much more. This talk offers hypotheses that address a key question for anthropogeny: How did biological evolution yield humans with the “construction-ready brains” and bodies that made us capable of the cultural evolution that created the diversity of our mental and physical constructs that we know today? Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40161]

Elizabeth Blackburn, Ph.D., examines the relationship between telomeres, cellular aging, and metabolic health, highlighting how telomere regulation differs between insulin-sensitive and insulin-resistant individuals. She discusses the effects of environmental factors—like glucose levels, stress hormones, and drugs—on telomere maintenance, which can disrupt cellular coordination and contribute to age-related diseases. Blackburn also shares insights from studies on hibernating lemurs, indicating that while their telomere health remains stable during metabolic slowdowns, it declines upon reactivation. Ultimately, she suggests that telomere maintenance could serve as a valuable biomarker for early signs of metabolic dysfunction, informing strategies for long-term health and resilience. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39944]

Artist Jeff Koons is renowned for his provocative and often kitschy sculptures that blend pop culture, consumerism, and art history. His works often feature oversized and glossy renditions of everyday objects, from balloon animals to household items, challenging the boundaries between high and low art while eliciting questions about mass production and cultural value. Koons talks with Kathryn Kanjo, director & CEO of the Museum of Contemporary Art San Diego, about his evolution as an artist, from simple inflatable rabbits to large-scale metal sculptures. [Arts and Music] [Show ID: 39155]

This talk provides a deep time perspective for assessing the behavioural implications of the creation of the earliest known structure and the technologies used in its making. Evidence for the earliest structure appears relatively late, about 500,000 years ago in Zambia, and before the evolution of Homo sapiens. The next oldest structures were made by Neanderthals in Europe, 176,000 years ago. The site in Zambia preserves rare evidence for the shaping and fitting together of two tree trunks to make a stable framework. The process of combining parts to make a whole reflects a conceptually new approach to technology, one which remains central to everything we make as humans, including structures. Did the invention of combinatorial technology require the use of language to discuss and evaluate diverse ways to form new constructs and constructions? This question arises from the extended planning and expertise needed in the making of combinatorial tools.    Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40160]

Dennis O. Clegg, Ph.D., discusses treatments for age-related macular degeneration (AMD), a condition that causes vision loss. Clegg explains that while patients often report improved vision after receiving implants, objective tests don't always confirm this. He explores the potential differences in patients' responses based on genetics and disease progression. There is also an ongoing challenge in finding the best ways to reduce immune rejection of these treatments. New trials are underway to test implants in earlier stages of the disease, and researchers are looking at different strategies like localized immunosuppression. Additionally, some studies suggest that secretions from retinal cells may help preserve vision. Overall, there are many open questions, but advances in the field offer hope for better AMD treatments. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39459]