Despite the rising prevalence of kidney stones in the U.S. over the past three decades, there hasn’t been much drug development to help prevent them. Dr. Thomas Chi of the University of California, San Francisco’s Department of Urology says while there haven’t been many successful treatment options, new surgical strategies have done amazingly well.
"It used to be that you'd have to have a giant open surgery, to open the kidney in order to get the stones out, and you'd lose a lot of kidneys that way, and a lot of blood loss. Nowadays, we have lots of minimally invasive options, most of those we specialize here at UCSF, and that includes shockwave therapy, small cameras that go into the kidney to use lasers to break up stones. And for really large stones, we can just make a small incision about a dime-size in your back, to go in and grind up stones. So the days of open surgery are pretty much over nowadays."
Chi is working to better understand how stones form, which he hopes will lead to new drug therapies in the future.
"So, we’re doing pretty good on the surgery front, but we really want to prevent people from getting stones in the first place."