Ukraine gets U.S. approval to fire long-range missiles into Russia, raising the stakes in a war that's entering a harsh winter. President Biden pushes his climate agenda at the G20 summit in Brazil, seeking to solidify U.S. leadership as allies prepare for President-elect Trump's return. And, Trump's plan to combat the fentanyl crisis sparks debate over whether tougher crackdowns on traffickers will help or harm efforts to save lives.

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Today's episode of Up First was edited by Andrew Sussman, Tara Neill, Andrea DeLeon, Mohamad ElBardicy, and Alice Woelfle.
It was produced by Ziad Buchh, Nia Dumas and Milton Guevara.
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