Award-winning journalist and pilot Miles O’Brien has spent over three decades bringing science, space, and technology stories to the public through CNN, PBS NewsHour, NOVA, and more. In this episode of Under Pressure, Miles shares his remarkable career journey, from covering shuttle launches to flying planes, and the story of how a seemingly minor injury turned into acute compartment syndrome, ultimately costing him his left arm.

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In this episode, Dr. Jonathan Sackier sits down with Dr. Jeff Gadsden, Professor of Anesthesiology and Chief of Orthopedic, Plastic, and Regional Anesthesiology at Duke University Medical Center. Together, they explore the ongoing controversy around using nerve blocks in patients at risk for acute compartment syndrome, the importance of timing and pressure monitoring, and how technology is reshaping the safety profile of these interventions.

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Read the studies discussed in this episode:

• Lower Extremity Peripheral Nerve Blocks for Patients at Risk for Acute Compartment Syndrome
• Awake spinal anesthesia facilitates spine surgery in poor surgical candidates: A case series
• Awake Spinal Fusion Is Associated with Reduced Length of Stay, Opioid Use, and Time to Ambulation Compared to General Anesthesia
• Single-shot interscalene block with liposomal bupivacaine vs. non-liposomal bupivacaine in shoulder arthroplasty

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In this episode of Under Pressure, host Dr. Jonathan Sackier sits down with Dr. Niloofar Dehghan, orthopaedic trauma surgeon, educator, and research powerhouse. From her pioneering work on weight-bearing protocols and flail chest fixation to her leadership in randomized trials and DEI initiatives, Dr. Dehghan shares what it means to challenge norms, both in and out of the OR. We cover the fundamentals of compartment syndrome, the evolving role of continuous pressure monitoring, her vision for a more inclusive future in orthopaedics, and the mindset needed to lead through evidence.

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Read the study reviewed in this episode:

Operative vs Nonoperative Treatment of Acute Unstable Chest Wall Injuries: A Randomized Clinical Trial

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In this episode of Under Pressure, Dr. Jonathan Sackier is joined by Dr. Charles Moon, Director of Orthopaedic Trauma at Cedars-Sinai Medical Center. Educator, researcher, and surgeon, Dr. Moon shares how structured protocols and objective data are transforming compartment syndrome diagnosis — and improving trauma care at every level.

Whether you’re in trauma surgery, acute care, or just curious about how innovation actually gets adopted in high-stakes medicine, this one’s for you.

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In this episode of Under Pressure, host Dr. Jonathan Sackier welcomes Dr. Hans Van Lancker, Network Chief of Orthopedics at Cambridge Health Alliance, to discuss how standardization, data, and real-time monitoring are reshaping the future of trauma care. From protocolized pathways in compartment syndrome to cutting length of stay by 150%, Dr. Van Lancker shares actionable strategies for improving patient outcomes while scaling system-wide efficiency.

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In this episode of the Under Pressure podcast series, we're joined by Pr. Mohamed (Mo) Imam, Consultant Trauma, hand, wrist, and upper limb surgeon at Rowley Bristow Orthopaedic Unit, Ashford and St Peter’s Hospitals. Pr. Imam discusses his pioneering work in digital health, his experience with sports medicine, and how various technologies can improve clinical care.

Read the paper reviewed in this episode:

• Transforming the NHS through AI-driven solutions: a new era of digital health
• Intersection of artificial intelligence, microbes, and bone and joint infections: a new frontier for improving management outcomes

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In this episode of Under Pressure, host Dr. Jonathan Sackier sits down with Charles Allan, founder and CEO of MY01. From growing up in an entrepreneurial family to launching a groundbreaking medical device, Charlie shares the full origin story of MY01 and the journey of bringing continuous pressure monitoring to life. Tune in to hear lessons learned, challenges faced, and what the future holds for medtech innovation.

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Welcome with us Pr. Peter Giannoudis, Professor and Chair of Trauma and Orthopaedics at the University of Leeds. With over 800 peer-reviewed publications, Pr. Giannoudis is a leader in orthopaedic trauma research and clinical practice. We’ll be discussing his latest study on risk factors for acute compartment syndrome, insights into treating open fractures, acute bone loss, and the impact of compartment syndrome in athletes. Join us as we explore how his passion for running ties into his research on trauma and compartment syndrome.

Read the article discussed during this episode:

Risk factors for acute compartment syndrome in one thousand one hundred and forty seven diaphyseal tibia fractures

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Join us for a captivating conversation with Mr. Ash Vasireddy, orthopedic and trauma surgeon at King's College Hospital and Cleveland Clinic London. Mr. Vasireddy shares insights on improving trauma care through lessons from aviation, the complexities of diagnosing compartment syndrome, and the role of patient education apps in reducing complications. Listen in on an in-depth discussion, practical guidance, and innovative perspectives on enhancing trauma care.

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In this episode of Under Pressure, we are joined by Angie Chisolm, President and Managing Partner of Optimal Healthcare Advisors. With a deep background in trauma program management and healthcare consulting, Angie brings her expertise to the forefront as we explore the complexities of trauma care. We'll dive into the leading causes of trauma-related deaths, the impact of funding on care quality, and how performance improvement initiatives can help reduce costs and improve patient outcomes. Don’t miss this insightful conversation!

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⁠⁠⁠https://www.underpressure.fm/⁠