Unlocking Myasthenia gravis

Episode 15 – Professor Francesco Saccà joins Professor Nils Erik Gilhus to delve into the pathophysiology of MG, discussing the role of the complement system, what determines whether MG is a fully reversible disease, and the necessity of accurate biomarkers for personalised care. They also discuss the different contributions of T and B cells to MG and how these may impact the success of targeted treatments.

Episode 14 – Cell-based diagnostic assays now available for MG are more sensitive than previous assays, but “are they as specific?” Professor Nils Erik Gilhus and Dr Gregorio Spagni discuss sensitivity and specificity of these new assays, as well as cost and ease of use.

Episode 13 – Professor Jan De Bleecker joins Professor Nils Erik Gilhus to reflect on EAN 2024 and discuss key congress highlights, including information on therapeutic advances in MG.

Professor Nils Erik Gilhus welcomes Professor Ernestina Santos to discuss late-onset MG, including the definition of late onset versus early onset, diagnostic and treatment challenges, and physical activity recommendations for these patients.

Professor Tarek Sharshar joins Professor Nils Erik Gilhus to discuss the use of steroids in people with MG, including dose recommendations, and treatment in the intensive care setting.

Professor Nils Erik Gilhus welcomes Dr Sarah Hoffmann to discuss the challenge of unmet treatment needs in MG, particularly for subgroups under-represented in clinical trials, including those who are older, pregnant, or seronegative.

Dr Christiane Schneider-Gold joins Professor Nils Erik Gilhus to discuss pregnancy in people with MG, including special precautions for delivery and the risk of transient neonatal MG.

Professor Benedikt Schoser joins Professor Nils Erik Gilhus to discuss the challenge of diagnostic delay in people with MG covering possible reasons for delays and recommended clinical tests.

“It’s a matter of finding the right exercise type, based on the personality.” Professor Anna Rostedt Punga joins Professor Nils Erik Gilhus to discuss the benefits of physical therapy in people with myasthenia gravis, how to deal with more complex cases and the importance of educating patients.

“Changes in antibody concentrations should influence your therapeutic decision.” Professor Nils Erik Gilhus is joined by Professor Marc De Baets to discuss the importance of regularly measuring autoantibodies to support treatment decisions in people with MG.