Malaria control requires an integrated approach with an emphasis on prevention and prompt treatment with effective antimalarials. This presentation will review some of the key points of the WHO Guidelines for the Treatment of Malaria and the key elements of the Global Malaria Action Plan. Key interventions to control malaria include: prompt and effective treatment with artemisinin-based combination therapies; use of insecticidal nets by people at risk; and indoor residual spraying with insecticide to control the vector mosquitoes