Fresh from Innovate 2025 in New York, we sat down with founders, operators, and agency leaders to ask the questions sellers care about most: which categories are worth launching now, how AI actually drives profit instead of noise, and what Amazon could change to help brands grow. The answers are bold, specific, and grounded in real P&L pressure—not theory.
We dig into the case for recurring revenue—beauty, supplements, consumables, pets, and baby—along with a contrarian stance to avoid high-risk verticals until you have capital and chops. Guests make the design-first argument too: pick any niche where you can truly improve the product and packaging, then use TikTok-friendly, demonstrable content to fuel demand. On the operations side, AI transforms the workflow: listing overhauls in seconds, campaign copilots surfacing first-party insights, CTR and CVR image audits across entire niches, and creative flywheels that turn out high-quality photos and video at scale. The pattern is clear—teams that train VAs on modern AI tools and measure outcomes with contribution profit outpace those chasing hacks or vanity ACOS.
We also press on fees, support, and seller experience. Referral fees, storage, and inbound placement fees draw heat for crushing margins, while newcomers struggle with complex FBA onboarding and fragmented internal communication. Guests call for better agency partnerships and, yes, more real humans in support. Tactic-wise, we separate signal from hype: DSP without attribution, sloppy AI images, and broad conquesting burn cash; sponsor brand video with aggressive creative testing, disciplined negative matching on autos, and price–ad spend harmonization unlock profit. Myths fall quickly: Amazon isn’t passive, it isn’t “too late,” and hacks don’t scale. As for 2026 acquisition, the room splits—TikTok’s algorithm and low CAC versus Amazon’s purchase intent and smoother path to checkout—hinting that channel mastery, not platform loyalty, will win.
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