In this episode of the Veterinary Cancer Pioneers Podcast, host Dr. Rachel Venable welcomes Dr. Steve Dow, professor of immunology at Colorado State University and Director of the Center for Immune and Regenerative Medicine. Dr. Dow shares insights from his groundbreaking work on myeloid-targeted immunotherapies and the innovative use of repurposed, FDA-approved drugs like losartan, palladia, and propranolol in treating canine cancers such as osteosarcoma and brain tumors. He also discusses the development of tumor vaccines, promising adjuvant trial results, and the critical role dogs play as translational models in advancing human cancer therapies. The episode highlights the future potential of bispecific antibodies and CAR-T cell therapies in both veterinary and human oncology.

📝Transcripts are available at https://www.imprimedicine.com/podcast.

To learn more about ImpriMed Personalized Prediction Profile, please visit https://www.imprimedicine.com/ppp

Music Credit: Hazy by Beat Mekanik

In this episode of the Veterinary Cancer Pioneers Podcast, host Dr. Rachel Venable speaks with Dr. Steve Suter, a trailblazer in canine bone marrow transplantation, about his unexpected path into transplant research and the launch of the world's only academic bone marrow transplant program for dogs. Dr. Suter discusses the differences between autologous and allogeneic transplants, clinical protocols, and the emotional and logistical challenges behind this advanced treatment for canine lymphoma and leukemia. They delve into powerful case stories, donor matching hurdles, and the growing importance of early intervention and immunotherapy in veterinary oncology. Tune in to hear how Dr. Suter is reshaping cancer care for dogs—and why bone marrow transplants may offer new hope where traditional chemotherapy falls short.

📝Transcripts are available at https://www.imprimedicine.com/podcast.

To learn more about ImpriMed Personalized Prediction Profile, please visit https://www.imprimedicine.com/personalized-prediction-profile

Music Credit: Hazy by Beat Mekanik

In this episode of the Veterinary Cancer Pioneers Podcast, host Dr. Rachel Venable welcomes Dr. Duncan Lascelles, a distinguished professor at North Carolina State University and a leading expert in veterinary pain management and surgery. Dr. Lascelles explores the complex relationship between pain and cancer in veterinary patients, highlighting how both cancer and its treatments can cause significant discomfort—and how pain itself may even influence cancer progression. Together, they dive into findings from clinical and laboratory studies and share best practices for pain assessment and management. Dr. Lascelles also emphasizes the importance of early intervention, client education, and the profound impact of effective pain control on patient outcomes and quality of life. Tune in to gain a deeper understanding of how thoughtful pain management can shape the future of veterinary oncology.

📝Transcripts are available at https://www.imprimedicine.com/podcast.

To learn more about ImpriMed Personalized Prediction Profile, please visit https://www.imprimedicine.com/personalized-prediction-profile

Music Credit: Hazy by Beat Mekanik

In this episode of the Veterinary Cancer Pioneers Podcast, host Dr. Rachel Venable welcomes Dr. Mark Mamula, an immunologist and professor at Yale University School of Medicine, to discuss his groundbreaking work in canine cancer immunotherapy. Dr. Mamula shares how his background in autoimmune diseases led him to develop an experimental vaccine targeting EGFR and HER2 proteins in dogs with cancer. He explains the science behind this therapy, its clinical trial progress, and its potential to improve survival outcomes for cancers such as osteosarcoma and hemangiosarcoma. They also explore the challenges of bringing new therapies to veterinary medicine, the role of combination treatments, and the importance of accessible, cost-effective options for pet owners. Tune in for an insightful conversation on the evolving landscape of canine cancer treatment and the promising future of immunotherapy.

📝Transcripts are available at https://www.imprimedicine.com/podcast.

To learn more about ImpriMed Personalized Prediction Profile, please visit https://www.imprimedicine.com/personalized-prediction-profile

Music Credit: Hazy by Beat Mekanik

In this episode of the Veterinary Cancer Pioneers Podcast, host Dr. Rachel Venable welcomes Dr. William Culp, a professor of soft tissue surgery at UC Davis specializing in surgical oncology and interventional radiology. Dr. Culp shares his journey into veterinary medicine, the role of mentorship in his career, and his groundbreaking work in interventional oncology. They explore the evolving use of interventional radiology as a "fourth pillar" in oncology, discussing treatments like urethral stenting, prostate embolization, and liver tumor therapies. Tune in for an enlightening discussion on how these minimally invasive techniques are transforming options for veterinary cancer care.

📝Transcripts are available at https://www.imprimedicine.com/podcast.

To learn more about ImpriMed Personalized Prediction Profile, please visit https://www.imprimedicine.com/personalized-prediction-profile

Music Credit: Hazy by Beat Mekanik

In this episode of the Veterinary Cancer Pioneers Podcast, host Dr. Rachel Venable welcomes Dr. Joelle Fenger, a dedicated veterinary oncologist and clinician-scientist at Ethos Discovery. Dr. Fenger shares her unique insights on bridging the gap between research and patient care, discussing how her work at the intersection of science and practice shapes treatment strategies for companion animals with cancer. From her early training to recent studies, Dr. Fenger reflects on the challenges and rewards of her research, emphasizing the importance of evidence-based approaches in improving patient outcomes. Tune in to hear her journey and the impact of her work on the veterinary field.

📝Transcripts are available at https://www.imprimedicine.com/podcast.

To learn more about ImpriMed Personalized Prediction Profile, please visit https://www.imprimedicine.com/personalized-prediction-profile

Music Credit: Hazy by Beat Mekanik

In this episode of the Veterinary Cancer Pioneers Podcast, host Dr. Rachel Venable welcomes Dr. Theresa Fossum, a renowned veterinarian, surgeon, and CEO of Phoenix Animal Wellness and Dr. Fossum's Pet Care. Dr. Fossum shares her insights on the growing role of CBD products in veterinary care, emphasizing the importance of product quality and proper dosing for pets. She delves into the challenges of conducting clinical trials within corporate-owned hospital environments, highlighting the barriers to research and the critical need for larger multi-center studies. Dr. Fossum also explores how advancements in technology and AI are poised to transform veterinary diagnostics and streamline workflows, improving both care quality and efficiency. Tune in to gain a deeper understanding of the evolving landscape of veterinary medicine and the innovative solutions that are shaping its future.

📝Transcripts are available at https://www.imprimedicine.com/podcast.

To learn more about ImpriMed Personalized Prediction Profile, please visit https://www.imprimedicine.com/personalized-prediction-profile

Music Credit: Hazy by Beat Mekanik

In this episode of the Veterinary Cancer Pioneers Podcast, host Dr. Rachel Venable welcomes Dr. Mason, a leading figure in veterinary oncology and immunotherapy. Dr. Mason discusses her groundbreaking work at the University of Pennsylvania, where she leads the first canine cancer immunotherapy consortium backed by the Cancer Moonshot Initiative. With a background in immunology and extensive experience in developing innovative therapies for dogs with cancer, she highlights the importance of using canine models to better understand and accelerate human cancer treatments. The conversation delves into the complexities of tumor-immune system interactions, the evolution of immunotherapy, and exciting developments in off-the-shelf cellular therapies that could revolutionize treatment for both dogs and humans. Tune in to discover how veterinary science is paving the way for advancements in comparative oncology.

• PRE-medical Cancer Immunotherapy Network Canine Trials (PRECINCT): https://www.precinctnetwork.org/
• Vetigenics: https://vetigenics.com/

📝Transcripts are available at https://www.imprimedicine.com/podcast.

To learn more about ImpriMed Personalized Prediction Profile, please visit https://www.imprimedicine.com/personalized-prediction-profile

Music Credit: Hazy by Beat Mekanik

In this episode of the Veterinary Cancer Pioneers Podcast, Dr. Rachel Venable is joined by Dr. Chand Khanna, founder and board chair of Ethos Discovery, to explore the advancements in comparative oncology. Dr. Khanna delves into the concept of Comparative Oncology 2.0, discussing the increasing collaboration between human and animal health companies. They also examine the challenges of clinical trials, regulatory hurdles, and the future potential of comparative oncology in accelerating cancer drug development. Dr. Khanna highlights key examples of successful transactions between animal health and biotech companies. The conversation reveals how veterinary oncology can significantly contribute to human cancer treatment breakthroughs. Tune in for a deep dive into cutting-edge veterinary cancer research.

• Citation mentioned in the episode: Fenger JM, Eward W, Hendricks W, McNiel E, Johannes C, et al. (2020) Delivering Innovation to Oncology Drug Development Through Cancer Drug DISCO (Development Incentive Strategy using Comparative Oncology): Perspectives, Gaps and Solutions. Ann med clin Oncol 3: 120. DOI: 10.29011/AMCO-120.000120 (https://www.gavinpublishers.com/article/view/delivering-innovation-to-oncology-drug-development-through-cancer-drug-disco-development-incentive-strategy-using-comparative-oncology-perspectives-gaps-and-solutions)

📝Transcripts are available at https://www.imprimedicine.com/podcast.

To learn more about ImpriMed Personalized Prediction Profile, please visit https://www.imprimedicine.com/personalized-prediction-profile

Music Credit: Hazy by Beat Mekanik

In this episode of the Veterinary Cancer Pioneers Podcast, host Dr. Rachel Venable welcomes Dr. Jolle Kirpensteijn, Chief Veterinary Officer at Hill's Pet Nutrition, to share his inspiring journey from aspiring fighter pilot to becoming a leader in veterinary surgical oncology. Dr. Kirpensteijn discusses the pivotal moments that shaped his career, including his transition from general veterinary practice to specializing in small animal surgery and his subsequent move into academia and industry. He highlights the importance of agility, open-mindedness, and risk-taking in oncology, as well as the evolving landscape of veterinary surgery, particularly the exciting advancements in minimally invasive and robotic surgery. Dr. Kirpensteijn also reflects on the value of continuous learning and embracing change to maintain passion in one's career. Tune in to hear his motivational insights and gain a deeper understanding of the dynamic field of veterinary oncology.

Check out Dr. Kirpensteijn's Podcasts:

• CatCafe Podcast (For Veterinary Professionals): https://catcafepodcast.net/
• PurrPodcast (For Pet Parents): https://purrpodcast.net/

📝Transcripts are available at https://www.imprimedicine.com/podcast.

To learn more about ImpriMed Personalized Prediction Profile, please visit https://www.imprimedicine.com/personalized-prediction-profile

Music Credit: Hazy by Beat Mekanik