Penn Jillette is one half of the magic duo Penn and Teller, who have the longest running show in the history of Vegas. Bill tries his best to get magicians' secrets out of Penn, and they discuss the love of humans vs. animals, the magic trick "blood from a stone," libertarians and seat belts, Penn being in the “nut chair” on Politically Incorrect, Bill’s opening joke on the Jerry Lewis telethon that almost got him cancelled, the problem with the brains of young people, Penn on hopping trains as a young man, when Bill was a nanny, and much, much more.