The CDC explains its reasoning behind lowering quarantine time for asymptomatic people infected with COVID-19. The year 2021 has been unusual for the auto industry as supply shortages drive up prices. And, legendary Hall of Famer John Madden legacy touched many generations of football lovers, he died suddenly at age 85.

Wednesday, December 29, 2021

NPR's Up First is the news you need to start your day. The three biggest stories of the day, with reporting and analysis from NPR News — in 10 minutes. Available weekdays at 6:30 a.m. ET, with hosts Leila Fadel, Steve Inskeep, Michel Martin and A Martinez. Also available on Saturdays at 9 a.m. ET, with Ayesha Rascoe and Scott Simon. On Sundays, hear a longer exploration behind the headlines with Ayesha Rascoe on "The Sunday Story," available by 8 a.m. ET. Subscribe and listen, then support your local NPR station at donate.npr.org.<br><br><em>Support NPR's reporting by subscribing to Up First+ and unlock sponsor-free listening. Learn more at plus.npr.org/upfirst</em>

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NPR's Up First is the news you need to start your day. The three biggest stories of the day, with reporting and analysis from NPR News — in 10 minutes. Available weekdays at 6:30 a.m. ET, with hosts Leila Fadel, Steve Inskeep, Michel Martin and A Martinez. Also available on Saturdays at 9 a.m. ET, with Ayesha Rascoe and Scott Simon. On Sundays, hear a longer exploration behind the headlines with Ayesha Rascoe on "The Sunday Story," available by 8 a.m. ET. Subscribe and listen, then support your local NPR station at donate.npr.org. Support NPR's reporting by subscribing to Up First+ and unlock sponsor-free listening. Learn more at plus.npr.org/upfirst

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