Jones and Keefe are joined by Dr. William Hahn, the William Rosenberg Professor of Medicine in the Department of Medical Oncology at Dana-Farber and Harvard Medical School and an Institute Member of the Broad Institute of MIT and Harvard. He serves as an Executive Vice President and the Chief Operating and Transformation Officer at Dana-Farber.

Jones and Keefe are joined by seven-year-old Lucas Leite, his mother Marcela, and nurse Meghan Deblois. Lucas and Marcela discuss his battle with Wilms tumor, the care he receives at the Jimmy Fund clinic, and the support system that Dana Farber provides for families.

Julie Fry and her nephew Liam join Jones and Keefe from the 2026 WEEI/NESN Jimmy Fund Telethon. Julie discusses her battle with stage IV endometrial cancer and the care she receives from Dana Farber.

Five-year-old Stanley Glowacki and his mother Meg join Jones and Keefe live at Fenway Park for 2026 WEEI/NESN Jimmy Fund Radio Telethon. Stanley and Meg discuss Stanely's battle with acute lymphoblastic leukemia, the care he receives at the Jimmy Fund Clinic, and his love for Spiderman

Dalia Ritvo is a 49-year-old from Denver, Colorado battling Li-Fraumeni syndrome and pancreatic cancer. Dalia describes what led her to Dana Farber from Colorado and the breakthrough care that she has received.

Everly Freitas, two years old battling optic pathway glioma, and her parents Michelle and Davin join the show.

Multiple Myeloma patient Kirk Shaeffer and Jacob Laubach from Dana Farber join the show

The owner of the Boston Celtics joins the show!

Sam Kennedy joins the show on the 24th annual Jimmy Fund Radio Telethon

Brian Hoyer and Bill Powers from Cambridge Mobile Telematics join the show