Week 13 may look light on paper, but several matchups carry major playoff weight — and we’re breaking down the 10 biggest games of the weekend with full analysis, stats, and against-the-spread picks.

Missouri travels to Oklahoma in a fascinating clash of elite defenses and shaky offenses. SMU and Louisville battle for ACC positioning, while USC heads to Oregon in a potential playoff elimination game. Arkansas tries to shock Texas in Austin, Kentucky looks to stay hot at Vanderbilt, and TCU aims to rebound against a surging Houston team. Pitt’s improving offense gets Georgia Tech’s vulnerable defense, Tennessee tries to break a 22-year curse in Gainesville, BYU pushes toward the Big 12 title game in Cincinnati, and Washington heads west to face UCLA in a matchup loaded with explosive potential.

We cover:

• 1:12 Missouri vs Oklahoma – Can Mizzou’s defense slow OU?
• 7:54 Louisville vs SMU – SMU’s defensive edge at home
• 13:05 USC vs Oregon – Ducks’ explosiveness vs USC’s porous D
• 18:38 Arkansas vs Texas – Motivation mismatch in Austin
• 23:33 Kentucky vs Vanderbilt – Wildcats chasing bowl eligibility
• 28:35 TCU vs Houston – Passing edge favors the Frogs
• 34:18 Pitt vs Georgia Tech – GT’s defense in trouble
• 40:45 Tennessee vs Florida – Vols try to end 22-year drought
• 47:48 BYU vs Cincinnati – BYU rolling toward Big 12 title shot
• 51:50 Washington vs UCLA – Huskies set up late-night fireworks

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