- Edwardsville (-4.5) @ O’Fallon OU 55.5
- Marquette (-2.5) @ Eureka OU 31.5
- Helias @ Cardinal Ritter (-9.5) OU 61.5
- St. Dominic @ Althoff (-7.5) OU 66.5
- Belleville East @ East St. Louis (-21.5) OU 60.5
- Parkway North @ Rockwood Summit (-9.5) OU 53.5
- Lindbergh @ Pattonville (-2.5) OU 40.5
- Ft. Zumwalt North (-12.5) @ Washington OU 48.5
- Ft. Zumwalt South @ Holt (-11.5) OU 46.5
- Howell Central @ Troy Buchanan (-9.5) OU 60.5
- Kirkwood (-6.5) @ Hazelwood Central OU 34.5
- Oakville (-4.5) @ Ladue OU 40.5
- Highland (-11.5) @ Mascoutah OU 58.5
- Triad @ Waterloo (-3.5) OU 48.5
- Lutheran St. Charles @ St. Mary’s (-13.5) OU 54.5
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