Science is giving us unprecedented insight into the big questions that have challenged humanity. Where did we come from? What is the ultimate destiny of the universe? What are the building blocks of the physical world? What is consciousness?

'What We Cannot Know' asks us to rein in this unbridled enthusiasm for the power of science. Are there limits to what we can discover about our physical universe? Are some regions of the future beyond the predictive powers of science and mathematics? Are there ideas so complex that they are beyond the conception of our finite human brains? Can brains even investigate themselves or does the analysis enter an infinite loop from which it is impossible to rescue itself?

To coincide with the launch of his new book of the same title, Marcus du Sautoy will be answering (or not answering) those questions