Dad and Milo discuss the weather... or more to the point, ALL weather—including what it is, what causes it, and the many different shapes and forms it can take. Milo welcomes his old friend Louise from the distant microclimate of San Francisco to debate temperature, seasons, and crazy weather experiences. Milo ends the show by quizzing Dad about the weather in cities across the globe.

Dad and Milo discuss the brain, including its various components and how it serves as the control center of the human body. Milo's grandmother (Nini) joins us in studio for a riveting interview about special brain powers, the importance of learning, and what you can do to keep your brain smart and healthy. Milo and Dad end the show by swapping brain teasers, including a cliffhanger that listeners are encouraged to ponder. Submit your answers for a chance to appear on the next episode!

Dad and Milo discuss basketball, including the sport's rules, history, and global cultural reach. Milo's cousins Sam and Eve join the show to talk about their favorite teams and players, and to explore how basketball and other sports impart valuable life lessons. Milo ends the show with a moving tribute to the importance of fairness in sports and life.

Dad and Milo discuss pandas—including their taxonomy, ecology, and behavior—and what it means to be an endangered species. Milo's friend Anders joins the show to offer insights on whether pandas would make good pets, and reveals his fascination with another endangered animal. Dad shares a story about his harrowing real-life encounter with a red panda.

Dad and Milo discuss cookies—how they're made, how long they've been around, and how many different kinds there are. Milo's friends Charlotte and Max discuss their favorite cookies to make, and offer insights into what makes the perfect cookie.

Dad and Milo discuss the planet Earth, its place in our solar system, and the physics of planetary revolution and rotation. Milo's friend Ruby shares her expertise on gravity, space travel, and what we can do to help protect Earth.

In the inaugural episode, Milo and Dad discuss the country of Israel. Bubbie makes an appearance.