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In this episode, we break down the gut-brain axis—the complex communication network that regulates hunger, metabolism, and body weight. We explore how the brain integrates signals from fat tissue, nutrients, nerves, and gut hormones like GLP-1 and CCK to control appetite and energy balance. From classic obesity research to modern discoveries about vagal signaling, nutrient sensing, and incretin hormones, we uncover how the body normally maintains weight—and why highly palatable foods and modern environments can override these systems.

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STUDIES: 

• Hypothalamic Control of Feeding 
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• Brain Glucose & Nutrient Sensing
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• Vagal Nutrient Signaling
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• CCK and Gut Satiety Signaling
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• Incretin Effect
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• GLP-1 Regulation of Feeding
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