Sign up to save your podcasts
Or
Share The VALidity Podcast
Share to email
Share to Facebook
Share to X
Share to email
Share to Facebook
Share to X
Or
The VALidity Podcast
By Valentina RodriguezHealth & Fitness
The VALidity Podcast episodes
- Retatrutide Explained | Peptide Series Pt. 1
Send us Fan Mail
Welcome to Part 1 of our Peptide Series, where we break down the science behind today’s most talked-about compounds–starting with retatrutide.
In this episode, we dive into the mechanism of action of retatrutide, the first GLP-1, GIP, and glucagon triple agonist, and why it represents a major shift in obesity pharmacology.
We cover:
- What GLP-1, GIP, and glucagon receptors actually do
- How retatrutide drives satiety, insulin signaling, and energy expenditure simultaneously
- Why adding glucagon changed the game
- A clear breakdown of the clinical trial data so far
- How retatrutide compares to current drugs like semaglutide and tirzepatide
This episode is your mechanism-first foundation for understanding where peptide-based fat loss is headed.
1:1 COACHING:
- email: [email protected]
SHOP MY NEW 'NUTRITION NAVIGATED' E-BOOK!
- https://vallfitt.squarespace.com/programs-guides/p/nutrition-navigated
STRENGTH & HYPERTROPHY TRAINING PROGRAM:
- https://vallfitt.squarespace.com/programs-guides/p/12-week-strength-hypertrophy-program
MY SOCIALS:
- IG:@Vallfitt_ifbbpro
- Tiktok: @Vallfitt
- YouTube: VallFitt
CONTACT ME:
- [email protected]
- IG: @TheValidityPodcast
STUDIES/CLINICAL TRIALS:
- PMID: 37366315
- PMID: 37385280
- PMID: 41090431
- PMID: 38367045
Support the show
34 min - Your Gut Is Controlling Your Body Weight
Send us Fan Mail
In this episode, we break down the gut-brain axis—the complex communication network that regulates hunger, metabolism, and body weight. We explore how the brain integrates signals from fat tissue, nutrients, nerves, and gut hormones like GLP-1 and CCK to control appetite and energy balance. From classic obesity research to modern discoveries about vagal signaling, nutrient sensing, and incretin hormones, we uncover how the body normally maintains weight—and why highly palatable foods and modern environments can override these systems.
1:1 COACHING:
- email: [email protected]
SHOP MY NEW 'NUTRITION NAVIGATED' E-BOOK!
- https://vallfitt.squarespace.com/programs-guides/p/nutrition-navigated
STRENGTH & HYPERTROPHY TRAINING PROGRAM:
- https://vallfitt.squarespace.com/programs-guides/p/12-week-strength-hypertrophy-program
MY SOCIALS:
- IG:@Vallfitt_ifbbpro
- Tiktok: @Vallfitt
- YouTube: VallFitt
CONTACT ME:
- [email protected]
- IG: @TheValidityPodcast
STUDIES:
- Hypothalamic Control of Feeding
- PMID: 14854036
- Brain Glucose & Nutrient Sensing
- PMID: 6105849
- PMID: 12032106
- PMID: 16511493
- PMID: 16902086
- Vagal Nutrient Signaling
- PMID: 32416069
- CCK and Gut Satiety Signaling
- PMID: 9729561
- PMID: 10592336
- PMID: 11397870
- PMID: 11247965
- PMID: 10812017
- Incretin Effect
- PMID: 3525546
- GLP-1 Regulation of Feeding
- PMID: 8538742
- PMID: 8897973
- PMID: 23549697
- PMID: 24569379
- PMID: 20522593
- PMID: 26440889
- PMID: 21368082
Support the show
31 min - Sleep is Anabolic
Send us Fan Mail
You don’t grow in the gym, you grow when you sleep. Every night your body has a built-in anabolic window. In this episode we break down how growth hormone secretions respond to sleep, and what that means for your physique goals.
1:1 COACHING APPLICATION:
- https://rvqfi1u3k06.typeform.com/to/VLXmxybS
SHOP MY NEW 'NUTRITION NAVIGATED' E-BOOK!
- https://vallfitt.squarespace.com/programs-guides/p/nutrition-navigated
STRENGTH & HYPERTROPHY TRAINING PROGRAM:
- https://vallfitt.squarespace.com/programs-guides/p/12-week-strength-hypertrophy-program
MY SOCIALS:
- IG:@Vallfitt_ifbbpro
- Tiktok: @Vallfitt
- YouTube: VallFitt
CONTACT ME:
- [email protected]
- IG: @TheValidityPodcast
STUDY:
- PMID: 40562026
Support the show
15 min - Navigating Flexibility While Dieting
Send us Fan Mail
What does balance really look like — and is true balance even possible? In this episode, I share how I personally navigate flexibility while chasing my physique goals. Spoiler alert: balance looks different for everyone, but I break down what works for me and give you practical, actionable tips to help you find your own version of balance.
1:1 COACHING APPLICATION:
- https://rvqfi1u3k06.typeform.com/to/VLXmxybS
'NUTRITION NAVIGATED' E-BOOK!:
- https://vallfitt.squarespace.com/programs-guides/p/nutrition-navigated
STRENGTH & HYPERTROPHY TRAINING PROGRAM:
- https://vallfitt.squarespace.com/programs-guides/p/12-week-strength-hypertrophy-program
MY SOCIALS:
- IG:@Vallfitt_ifbbpro
- Tiktok: @Vallfitt
- YouTube: VallFitt
CONTACT ME:
- [email protected]
- IG: @TheValidityPodcast
DIET BREAK/ REFEED STUDIES:
- DOI:10.1080/15502783.2025.2550185
- DOI:10.13140/RG.2.2.20065.11362
- DOI:10.1080/15502783.2025.2550187
- DOI:10.1080/15502783.2025.2550187
Support the show
26 min - Reverse Dieting Beyond the Scale
Send us Fan Mail
In this episode, we dive into the qualitative findings from our USF Reverse Dieting Study to compare how three post-diet paths—reverse dieting, straight to maintenance, and a looser/intuitive return—actually feel. We cover hunger, fullness, adherence, energy, training performance, etc. If you missed Part 1’s numbers on weight regain trends, catch that first then come back for the human side of the data.
1:1 COACHING APPLICATION:
- https://rvqfi1u3k06.typeform.com/to/VLXmxybS
CONTACT ME:
- [email protected]
- IG: @TheValidityPodcast
STRENGTH & HYPERTROPHY TRAINING PROGRAM:
- https://vallfitt.squarespace.com/programs-guides/p/12-week-strength-hypertrophy-program
MY SOCIALS:
- IG:@Vallfitt_ifbbpro
- Tiktok: @Vallfitt
- YouTube: VallFitt
STUDIES:
- DOI:10.1080/15502783.2025.2550185
- DOI:10.13140/RG.2.2.20065.11362
- DOI:10.1080/15502783.2025.2550187
- DOI:10.1080/15502783.2025.2550187
Support the show
21 min - Does Reverse Dieting Work? (How to keep weight off) - Pt 1
Send us Fan Mail
We’ve all heard about reverse dieting… but does it actually work? This week, we dive into early data from our research at USF – the world’s first reverse diet intervention study – looking at how different post-dieting approaches impact weight regain after a diet.
1:1 COACHING APPLICATION:
- https://rvqfi1u3k06.typeform.com/to/VLXmxybS
CONTACT ME:
- [email protected]
- IG: @TheValidityPodcast
STRENGTH & HYPERTROPHY TRAINING PROGRAM:
- https://vallfitt.squarespace.com/programs-guides/p/12-week-strength-hypertrophy-program
MY SOCIALS:
- IG:@Vallfitt_ifbbpro
- Tiktok: @Vallfitt
- YouTube: VallFitt
STUDIES:
- DOI:10.1080/15502783.2025.2550185
Support the show
31 min - GLP-1: 101 (+ starting my PhD program)!
Send us Fan Mail
WELCOME BACK! In this episode, I share an inside look at the start of my PhD journey at Vanderbilt University — from settling into Nashville to diving into our first big projects in the lab. We also unpack some of the latest research on GLP-1s, exploring exciting new findings and what they could mean for those who don't currently respond to GLP-1 treatment
1:1 COACHING APPLICATION:
- https://rvqfi1u3k06.typeform.com/to/VLXmxybS
CONTACT ME:
- [email protected]
- IG: @TheValidityPodcast
STRENGTH & HYPERTROPHY TRAINING PROGRAM:
- https://vallfitt.squarespace.com/programs-guides/p/12-week-strength-hypertrophy-program
MY SOCIALS:
- IG:@Vallfitt_ifbbpro
- Tiktok: @Vallfitt
- YouTube: VallFitt
Support the show
23 min - Menopause & Reverse Dieting with Dr. Bill Campbell
Send us Fan Mail
Our favorite guest is back!! Dr. Bill Campbell (DBC) joins us with updates on his menopause research and our Reverse Dieting research. As a lifelong fat loss researcher, Dr. Campbell has transitioned his focus from the general population to fit peri-menopausal women struggling to lose weight. In today's episode we talk about the upcoming research he is conducting on this population, as well as the findings from our reverse diet study.
1:1 COACHING APPLICATION:
- https://rvqfi1u3k06.typeform.com/to/VLXmxybS
CONTACT ME:
- [email protected]
- IG: @TheValidityPodcast
STRENGTH & HYPERTROPHY TRAINING PROGRAM:
- https://vallfitt.squarespace.com/programs-guides/p/12-week-strength-hypertrophy-program
MY SOCIALS:
- IG:@Vallfitt_ifbbpro
- Tiktok: @Vallfitt
- YouTube: VallFitt
DR. CAMPBELL'S SOCIALS:
- IG: @billcampbellphd
- YouTube: BillCampbellPhD
Support the show
1 hr 13 min - Nighttime Routines for Optimal Sleep
Send us Fan Mail
In this episode, we dive into the science-backed habits that can turn your evenings into a powerful reset for your body and mind that supports optimal quality sleep—your body’s most underrated fat loss enhancer. From sleep supplements to meal timing, I’m breaking down exactly what your nighttime routine needs to help you fall asleep faster, stay asleep longer, and wake up truly recovered.
1:1 COACHING APPLICATION:
- https://rvqfi1u3k06.typeform.com/to/VLXmxybS
Haze Sleep Powder (code VAL):
- https://pescience.com/products/haze-sleep-powder
Erase-Pro Cortisol Support (code VAL):
- https://pescience.com/products/erase-pro
MINICUT CHALLENGE IS OPEN NOW
- https://vallfitt.squarespace.com/programs-guides/health-hardwired-challenge
RAPID RESET INTEREST FORM
- https://docs.google.com/forms/d/e/1FAIpQLSd_TAwquyE-yPguoNRQgBIqm2ZkgNK3kGPVkWRGdZcYUWnKZQ/viewform?usp=dialog
SHOP MY NEW 'NUTRITION NAVIGATED' E-BOOK!
- https://vallfitt.squarespace.com/programs-guides/p/nutrition-navigated
CONTACT ME:
- [email protected]
- IG: @TheValidityPodcast
STRENGTH & HYPERTROPHY TRAINING PROGRAM:
- https://vallfitt.squarespace.com/programs-guides/p/12-week-strength-hypertrophy-program
MY SOCIALS:
- IG:@Vallfitt_ifbbpro
- Tiktok: @Vallfitt
- YouTube: VallFitt
STUDIES:
- Sleep studies:
- PMID: 40236824
- PMID: 35458110
- PMID: 36272396
- Magnesium study:
- PMID: 36899275
- L-theanine study:
- https://doi.org/10.1016/j.smrv.2025.102076
- Glycine study:
- PMID: 37851316
- Mouth tape study:
- PMID: 36141367
Support the show
33 min - Upgrade Your Morning Routine
Send us Fan Mail
We hear it all the time: “Win the morning, win the day.” But what does that actually look like—physiologically and practically? In this episode, I’m breaking down the exact structure of a high-performance morning routine through the lens of physiology and psychology. From movement to momentum, here’s how to set yourself up for success—before the day even begins.
MINICUT CHALLENGE IS OPEN NOW
- https://vallfitt.squarespace.com/programs-guides/health-hardwired-challenge
Versalyte Charged (code VAL):
- https://pescience.com/products/versalyte-charged
L-Carnitine (code VAL):
- https://pescience.com/products/trucarnitine
RAPID RESET INTEREST FORM
- https://docs.google.com/forms/d/e/1FAIpQLSd_TAwquyE-yPguoNRQgBIqm2ZkgNK3kGPVkWRGdZcYUWnKZQ/viewform?usp=dialog
1:1 COACHING APPLICATION:
- https://rvqfi1u3k06.typeform.com/to/VLXmxybS
SHOP MY NEW 'NUTRITION NAVIGATED' E-BOOK!
- https://vallfitt.squarespace.com/programs-guides/p/nutrition-navigated
CONTACT ME:
- [email protected]
- IG: @TheValidityPodcast
STRENGTH & HYPERTROPHY TRAINING PROGRAM:
- https://vallfitt.squarespace.com/programs-guides/p/12-week-strength-hypertrophy-program
MY SOCIALS:
- IG:@Vallfitt_ifbbpro
- Tiktok: @Vallfitt
- YouTube: VallFitt
STUDIES:
- PMCID: PMC7492403
- PMCID: PMC2908954
- PMID: 10751106
Support the show
24 min
About The VALidity Podcast
From the publisher's feed
The VALidity podcast discusses and educates on scientific topics relevant to your health and fitness. Valentina Rodriguez earned her Master's degree in Exercise Science with a concentration in…
Physique Enhancement from USF while working under Dr. Bill Campbell as his research coordinator. This podcast brings you everything she learned–basically a free master's education!!
Every week, she'll cover new topics in training, nutrition, fat loss, muscle gain... really anything that could be pertinent to your fitness goals.
We get into the concepts, the research, the nitty gritty science so come ready to learn.
Every week, she'll cover new topics in training, nutrition, fat loss, muscle gain... really anything that could be pertinent to your fitness goals.
We get into the concepts, the research, the nitty gritty science so come ready to learn.