Track 3:

 

Immunotherapy

 

Late 1800's in NY - hospital - Dr. Cooler

 

Would inject streptococcus bacteria straight into the tumor

He didn't document everything well according to colleagues

After his death, his daughter discovered boxes of reports about every patient - she published them

12%-15% of patients survived

 

Early 20th Century - scientists tried that with viruses

 

Gary explained research with viruses in vitro

 

Immunotherapy - using antibodies or using white blood cells

 

Basics of Immunotherapy

 

Antibody is y-shaped (can also bind to proteins - compliment proteins)

 

FC-Fragment binds to lymphocytes