In this episode, Dr. Dan and Justine introduce their 'Central Sensitization Algorithm' designed to help healthcare providers diagnose and treat central sensitization and related neuroinflammatory disorders more effectively. The algorithm categorizes symptoms into distinct buckets of nervous system dysfunction, allowing providers to more quickly and efficiently identify and prioritize their treatment plan. By addressing potential pre-existing diagnoses and symptoms, the sensitization algorithm aims to better streamline assessments and improve outcomes for complex patients by creating a clearer picture of an otherwise confusing presentation. The episode highlights the importance of this tool in reducing diagnostic frustration and inadvertent harm, while also empowering patients to better understand and communicate their symptoms.

References:

www.iniyh.com

Timestamps:

00:00 Official Intro

00:17 Intro - How you start to think about it

01:31 Initial Presentation

03:25 Neuropathic / Nociceptive

04:01 Central Sensitization (Other side)

04:45 What is Sensitization?

05:56 How Dan Got Into Hypermobility

08:44 3 Components of Hypermobile EDS

09:18 Two Sides of Central Sensitization

11:03 Justine's Path to Central Sensitization

16:04 Dan's Frown of Frustration

18:57 Looking at the Literature

20:32 7 Main Categories of CS

22:14 Pre-existing Diagnoses 

22:37 Disproportionate, prolonged pain

24:24 Symptoms

25:30 Sensory Hypersensitivity

30:22 Sleep Disturbance

34:38 Fatigue

36:47 Cognitive Impairment

40:02 Mood Disturbance

42:46 Motor Dysfunction

45:33 Dysautonomia - Cardiovascular

47:42 Dysautonomia - Gastrointestinal System

48:34 Dysautonomia - Urinary System

49:47 Dysautonomia - Secretor Motor System

50:49 Dysautonomia - Reproductive System

52:22 Assessment

54:31 What do we do as Doctors? What is driving this patient's CS?

57:57 Final Points

01:00:13 Disclaimer