We continue our series of discussions on the sociology of science and cover a seminal article that is commonly found as required reading in doctoral programs -- Thomas Gieryn’s 1983 article “Boundary-Work and the Demarcation of Science from non-Science” from the American Sociological Review. This commentary draws from three different historical case studies to explore where the boundary is between what is or should be considered science or the autonomy granted to scientists and what is considered other forms of intellectual pursuit. In Part 1, we explore the cases that involve competition between the world of science and those of religion and engineering, of true science vs. pseudo-science, and of scientific openness and collaboration vs. national security and commensurate need for secrecy.