Episode 381. Topic: Prediabetes. Theme: Diabetes. How does type II diabetes develop? What does prediabetes mean? Can this state be reversed? How common is prediabetes around the world?

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Episode 380. Topic: Type I diabetes. Theme: Diabetes. What is type I diabetes? How is it an autoimmune disease? What is the average age of diagnosis? Why are diagnosis rates increasing? 

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Episode 379. Investigating myself. Topic: Am I antisocial? How can genetics shape our behaviors and personality? How are variants in the gene MAO-A associated with aggressive behavior? Do I have the aggressive genetic association?!

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Methodology note: The SNP associated with MAO-A promoter repeat is rs909525.

Episode 378. Topic: FIRE. Theme: Retirement finance. How does one retire early? Is it difficult to save up the necessary investments for early retirement? What other ways can investment be used to lessen work later in life?

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Episode 377. Topic: Aging populations. Theme: Retirement finance. How are age ratios expected to change in the next century? Why does this matter? How can we keep social programs running with a smaller working population?

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Episode 376. Topic: Types of retirement funds in the US. Theme: Retirement finance. How can you invest for retirement? What kinds of investment accounts are out there and what are their pros and cons? How are retirement accounts different from regular investment accounts?

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Episode 375. Topic: Rise of the 401(k). Theme: Retirement finance. How old are pensions? Why are pensions uncommon today? What are the pros and cons of pensions and a 401(k) retirement investment account?

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Episode 374. Topic: Social security in the USA. Theme: Retirement finance. How was social security established? How does it work? How much can someone receive? How does it depend on retirement age?

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Episode 373. Investigating myself. Topic: CCR5. How does HIV immunity work? Do I have deletions in my CCR5 gene? How can I find this out?

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Methodology notes:
I searched the hg38 BAM file at chr3:46373450-46373488 (samtools view) for the deletion of GTCAGTATCAATTCTGGAAGAATTTCCAGACA. Reads contained the full sequence. I included a search for sequences with concatenated flanking nucleotides (indicating the deletion) but did not find any. I also searched unmapped reads. This strongly indicated that I am homozygous for the intact CCR5.  

Episode 372. Topic: Emerging viruses. Theme: Epidemiology. Where do new viruses come from? Did pre-agriculture humans experience viral diseases? How are viruses reemerging?

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