Episode 336. Investigating myself. Topic: Sex check. How is human sex determined? Is it always about XX and XY? In this episode, I use my DNA to check that I am, in fact, a biological female.
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Methodology notes:
SRY gene presence is determined by alignment. No reads aligning to any part of the SRY gene were detected in my genome. Chromosome copy number was inferred from the proportion of uniquely aligned reads normalized by chromosome size.