Malaria, a mosquito-borne infection, affects some 228 million people globally each year, killing over 400,000 of them—primarily children under the age of 5. In part one of a miniseries, Thomas Locke, host of the Johns Hopkins Malaria Research Institute podcast “Malaria Minute,” breaks down the parasite’s unique lifecycle which allows it to adapt rapidly to drugs and to our immune system’s efforts to fight it off. You can learn more about groundbreaking malaria research.