Dr Glenn McConell chats with Associate Professor from the University of Wisconsin-Madison, USA. Jill is an expert on the brain and exercise. We discussed the effect of acute (one bout) and chronic physical activity/ exercise on cognitive function, brain blood flow (BBF), dementia/Alzheimer’s disease risk and progression etc. A very interesting chat. Twitter: @Barnes_Lab
0:00. Introduction and welcome
2:01. How Jill got into exercise research
4:25. Studying with Hiro O. Tanaka
6:00. Researching with Michael Joyner
7:45. How measure brain blood flow (BBF)
10:00. Blood vessels that supply the brain and blood flow
19:16. What would look at if had unlimited funding?
20:32. BBF vs glucose use in the brain
21:30. Regional blood flow in the brain
22:40. Does BBF increase during exercise?
24:40. Blood pressure and regulation of brain blood flow
29:00. Effect of exercise intensity in BBF
32:25. Hypnosis/anticipatory rises in BBF
34:30. BBF distribution has not been examined much during exercise
37:00. Cognitive tests and BBF
38:00. Why does BBF decrease during very intense exercise?
41:00. Central fatigue and BBF
42:30. Exercise training and BBF
45:00. BBF and cognitive function
46:20. How quickly does BBF increase with exercise?
47:25. Fitness and BBF at rest
49:55. Cognition and exercise/lifestyle
51:44. Exercjse intensity and the brain
53:10. Resistance training and cognitive function
55:07. Exercise and brain endothelial function
57:10. Exercise and the risk of stroke
59:35. Exercise and the risk of dementia/Alzheimers disease
1:02:14. Exercise and mental health
1:03:45. Diet and BBF/brain health
1:06:15. Sex differences in BBF
1:12:57. Age and BBF
1:15:20. Fitness/strength and cognition etc
1:16:10. Erythropoietin, hemoglobin and cognitive function.
1:18:48. Exercise and myokines, BDNF, exosomes
1:21:10. Neurogenesis and exercise
1:22:20. Exercise, cognition and hypertension/diabetes
1:25:00. Prevention of Alzheimer’s disease/dementia
1:27:00. Exercise intensity and mode of exercise
1:29:55. BBF during resistance exercise
1:31:20. Controversies in the field
1:34:52. Keep things simple re exercise
1:37:00. Takeaway messages
1:39:57. Outro