Frazis Capital Podcast

#93: Retail Driving Red-Hot Rally & the $10B Quest for the Holy Grail: Can Grail Change Cancer Detection?


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0:00 – Intro: Mike & Ellianna catch up after Melbourne investor meetings

0:45 – Market update: Retail investors driving a red-hot rally

2:15 – Quants, institutions, and semiconductors hitting profit targets

3:40 – Why Frazis Capital is rotating into healthcare

4:30 – Spotlight on Grail: $10B spent chasing a pan-cancer blood test

6:10 – The Pathfinder 2 trial and physician skepticism

7:40 – FDA approval, adoption challenges, and cash burn9:00 – Clarity Pharmaceuticals: $203M raise and bold head-to-head trial

10:40 – Lessons from biotech cycles: Intellia’s 100% rebound

12:10 – Quant signals, timing, and managing risk in volatile markets

13:40 – Retail euphoria vs. institutional lag — what comes next?

15:10 – AI investment boom: data centers, semis, and software plays

17:00 – Byrna’s results & the “AI in everything” trend

18:20 – When hype meets fundamentals: the AMD-OpenAI deal

20:00 – Scaling out, profit-taking, and managing portfolio exposure

22:10 – Wrap-up and next week’s preview

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Frazis Capital PodcastBy Michael Frazis

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