A Journey Through Medicine

A Journey Through Medicine

By Shaun, Norm and TerenceMedicineHealth & Fitness
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A Journey Through Medicine episodes

  • 1.32. Diabetes: Pathophysiology and Complications (ft. Jonathan)

    Today the boys were joined by the legendary Jonathan as they discuss diabetes, a common chronic disease impacting millions worldwide.


    Content covered:

    - Diabetes insipidus

    - Glucose homeostasis (insulin + glucagon) including some biochemistry

    - Pathophysiology, diagnosis, clinical features and comparisons between Type 1 & 2 diabetes mellitus

    - Complications of chronic hyperglycaemia (vascular, neural and immune)

    - Hypoglycaemia


    39 min
  • 1.31: Managing Diabetes (ft. Claire)
    Claire takes us on a tour through the drugs used to treat diabetes - a condition that affects 1 in 10 people globally!!
    Content covered in this episode includes:
    - Insulin regimens for Type 1 Diabetes
    - (Some) novel treatments for Type 1 Diabetes
    - Diagnostic criteria for T2DM
    - Metformin
    - SGLT2 inhibitors
    - Incretin-based therapies (inc. GLP-1 agonists and DPP-4 inhibitors)
    - Sulfonylureas
    - Thiazolidinediones
    - a-glucosidase inhibitors
    - Bariatric surgery!
    34 min
  • 1.30: Cases of Glomerulonephritis and other Renal Diseases (ft. Jack)

    Welcome to our 30th episode!


    Celebrate this milestone with us by letting out your inner Sherlock Holmes and try crack these (expertly crafted) cases of glomerulonephritis and other renal diseases. Learn about the differential diagnosis of nephritic vs nephrotic syndromes, acute vs chronic renal failure and some other related conditions.

    53 min
  • 1.29. Renal Physiology: A Journey Through the Nephron (ft. Jack)
    Today the boys are joined by Jack as they discuss renal physiology! Essentially, how your kidneys regulate blood volume, electrolytes and pH homeostasis while getting rid of toxic substances we don’t need. This knowledge is key to understanding renal pathology and pharmacology.
    Content covered in this episode:
    - The different segments of the nephron and their functions
    - Homeostatic control of electrolytes and blood volume
    - The formation of urine
    - Renin-angiotensin-aldosterone system
    - ANP and ADH
    - Matabolic acid - base balance
    44 min
  • 1.28: Overview of Gastrointestinal Pharmacology (ft. Claire)
    Claire helps the boys out with the plethora of drugs that can be used to treat nausea, vomiting, reflux and more - and all their funky nuances.
    Topics covered in this episode include:
    - General causal pathways of nausea and vomiting
    - Drugs used to treat nausea and vomiting - including 5HT3 antagonists, dopamine antagonists (metoclopramide and prochlorperazine), domperidone, steroids, NK-1 antagonists (aprepipant and fosaprepipant), hyoscine and lorazepam
    - Prescribing nausea and vomiting drugs in special populations i.e. pregnancy and children
    - Drugs used to treat GORD and reflux symptoms
    - NOT EXAMINABLE: Drugs used to treat hepatic encephalopathy
    31 min
  • 1.27: Inflammatory Bowel Disease + Non-Neoplastic Diseases of the Small and Large Bowel (ft. Mike)

    Today the legendary Mike Kendall imparts some wisdom on the boys as they revise the pathogenesis, clinical features and what differentiates the inflammatory bowel diseases and other non-neoplastic conditions of the bowel.

    Content covered includes:
    - Crohn's disease and ulcerative colitis
    - Ischaemic colitis
    - Diverticular disease
    - Antibiotic-associated diarrhea and pseudomembranous colitis
    - Microscopic Colitis
    - Coeliac disease and its consideration in the differential diagnosis


    Correction: Ipilimumab can cause an Autoimmune-like enterocolitis, not GVHD.


    48 min
  • 1.26: Pathology of the Stomach
    Ben Earner accompanies the boys as their pathology journey through the GIT continues, this time diving head-first into the stomach!
    Content covered in this episode includes:
    - Gastritis and causes of gastritis
    - Atrophic gastritis
    - Peptic ulcer disease
    - Benign neoplastic or neoplastic-like gastric lesions including: gastric hyperplastic polyp, fundic gland polyp and adenoma
    - Gastric cancers including tubular/intestinal type, poorly cohesive/diffuse adenocarcinoma, MALT lymphoma and GIST
    25 min
  • 1.25: Pathology of the Oesophagus

    Retrosternal chest pain only has cardiac causes... right?


    In this episode, the lads welcome back Ben Earner as they try to make sense of the important pathologies affecting the oesophagus and the differing signs and symptoms these could manifest as.


    Content covered:

    - Signs/symptoms of oesophageal disease such as dyspepsia, dysphagia, odynophagia, waterbrash and the dreaded retrosternal chest pains

    - Functional and mechanical obstructive disorders eg Achalasia and Schatzki rings

    - Oesophageal Varices and portal hypertension

    - Gastro-oesophageal reflux disease (GORD/GERD): causes and consequences

    - Oesophagitis

    - Barrett oesophagus

    - Oesophageal adenocarcinoma

    - Oesophageal squamous cell carcinoma

    26 min
  • 1.24: Pulmonary Embolism & Hypertension
    In this episode, the lads revise the common pulmonary vascular diseases, and just how much can go wrong when you lose or impair that crucial part of your body's oxygen delivery mechanism.
    Content covered in this episode:
    - Embolisms and infarcts associated with the lungs
    - Pathogenesis of DVT and PE and associated risk factors
    - Pulmonary Hypertension: causes and classifications
    - Signs and symptoms of right-heart failure / cor pulmonale
    - Goodpastures syndrome and granulomatosis with pulmonary angiitis
    29 min

About A Journey Through Medicine

From the publisher's feed

Join second year medical students from Australia as they delve into the depths of medicine, documenting their experiences and what they learn week-to-week.