Knowing at which point in the course of disease progression a drug for geographic atrophy could be most effective may be key to unlocking a treatment paradigm if a drug is approved. What late-breaking data presented at the 2021 AAO annual meeting could help inform retina’s eventual strategy to treat GA? 

New Retina Radio spoke with David Lally, MD, about his presentation on a post hoc analysis of the GATHER1 study to learn more about how GA patients who received avacincaptad pegol (Zimura, IVERIC bio) progressed from nascent disease to more advanced disease. 

We also heard from Veeral Sheth, MD, MBA, about the phase 2b ALTISSIMO study, which explored the use of GB-102 (Graybug Vision) for the treatment of wet AMD. Just how long might a drug administered only twice a year provide relief to wet AMD patients? Stay with us to find out. 

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