Revelations 13:1

"The dragon stood on the shore of the sea. And I saw a beast coming out of the sea that had ten horns and seven heads, with ten crowns on its horns, and on each head a name of blasphemy."

It all comes down to this. The trio has arrived to their appointment with Lucifer right on time and they're going to have to rely on each other more than ever if they're going to get themselves, and humanity as we know it, out alive.