-Jacob was obeying the Lord to go back to Bethel, then tragedy:

“Leaving Bethel, Jacob and his clan moved on toward Ephrath. But Rachel went into labor while they were still some distance away. Her labor pains were intense. After a very hard delivery, the midwife finally exclaimed, “Don’t be afraid—you have another son!” Rachel was about to die, but with her last breath she named the baby Ben-oni (which means “son of my sorrow”). The baby’s father, however, called him Benjamin (which means “son of my right hand”). So Rachel died and was buried on the way to Ephrath (that is, Bethlehem). Jacob set up a stone monument over Rachel’s grave, and it can be seen there to this day.” 

- Genesis 35:16-20 NLT

“Then Jacob said to Simeon and Levi, “You have brought trouble on me by making me stink to the inhabitants of the land, the Canaanites and the Perizzites. My numbers are few, and if they gather themselves against me and attack me, I shall be destroyed, both I and my household.” But they said, “Should he treat our sister like a prostitute?” 

- Genesis 34:30-31 ESV

“And Jacob was left alone. And a man wrestled with him until the breaking of the day. When the man saw that he did not prevail against Jacob, he touched his hip socket, and Jacob’s hip was put out of joint as he wrestled with him. Then he said, “Let me go, for the day has broken.” But Jacob said, “I will not let you go unless you bless me.” And he said to him, “What is your name?” And he said, “Jacob.” Then he said, “Your name shall no longer be called Jacob, but Israel, for you have striven with God and with men, and have prevailed.”

- Genesis 32:24-28 ESV

“...and said to them, “I see that your father does not regard me with favor as he did before. But the God of my father has been with me. You know that I have served your father with all my strength, yet your father has cheated me and changed my wages ten times. But God did not permit him to harm me.” 

- Genesis 31:5-7 ESV

“And Jacob lifted up his eyes and looked, and behold, Esau was coming, and four hundred men with him. So he divided the children among Leah and Rachel and the two female servants. He himself went on before them, bowing himself to the ground seven times, until he came near to his brother. But Esau ran to meet him and embraced him and fell on his neck and kissed him, and they wept.”

- Genesis 33:1, 3-4 ESV

"I appeal to you therefore, brothers, by the mercies of God, to present your bodies as a living sacrifice, holy and acceptable to God, which is your spiritual worship. Do not be conformed to this world, but be transformed by the renewal of your mind, that by testing you may discern what is the will of God, what is good and acceptable and perfect."

 - Romans 12:1-2

"Why are you cast down, O my soul, and why are you in turmoil within me? Hope in God; for I shall again praise him, my salvation and my God. My soul is cast down within me..."

- Psalm 42:5-6

"Hope deferred makes the heart sick, but a desire fulfilled is a tree of life." 

- Proverbs 13:12

"Anxiety in a man’s heart weighs him down, but a good word makes him glad. "

- Proverbs 12:25

"Then he said to them, “Go your way. Eat the fat and drink sweet wine and send portions to anyone who has nothing ready, for this day is holy to our Lord. And do not be grieved, for the joy of the Lord is your strength.” 

- Nehemiah 8:10