Amazing Things Podcast

Amazing Things Podcast

By United For Medical ResearchArts
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Amazing Things Podcast episodes

  • Tissue Chips: The Greatest Technology You've Never Heard Of

    Precision medicine will be available to everyone because of Tissue Chips. Hear the fascinating story of the most important technology you have never heard of before. In this episode of the Amazing Things Podcast, brought to you by United For Medical Research, we take you inside the Tissue Chip program - an NCATS collaboration with the Defense Advanced Research Projects Agency and FDA to support the development of bioengineered devices to improve the process of predicting whether drugs will be safe or toxic in humans. 

    17 min
  • Preventing Pandemic: How Ebola Prepared America for Coronavirus

    The Ebola virus is a terrifying, rapidly fatal and until just recently untreatable disease with a mortality rate between 25% and 90%. In this episode of the Amazing Things Podcast, we take you inside the scientific discovery and the public-private partnership that turned the tide on Ebola and helped prepare America for the novel coronavirus. Featuring Dr. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases and Neil Stahl, Ph.D. of Regeneron Pharmaceuticals, Inc.

    12 min
  • NIH Funding and the Economic Impact in Rural States

    The importance of strong, sustainable annual funding for the National Institutes of Health (NIH) is known to states with major biomedical R&D hubs like California, Massachusetts, North Carolina and Texas. In these states there is a clear link between the NIH-funded research that occurs there and the state’s economy and job creation. But what about states where such a link might be less apparent? What is the impact in states that tend to be more rural than urban and that aren’t among the top recipients of NIH research funding?

    15 min
  • Sen. Roy Blunt: Medical Research is a National Priority
    Amazing Things Podcast: Newsmaker Edition. U.S. Senator Roy Blunt of Missouri is responsible for delivery four consecutive years of increased federal funding for biomedical research to the National Institutes of Health. Sen. Blunt, Chairman of the Senate Labor-HHS Appropriations Subcommittee, speaks candidly to Amazing Things about the promise of precision medicine and the bipartisan support behind funding America's investment in biomedical research.
    16 min
  • Rep. Tom Cole: NIH Budget Has To Grow
    Amazing Things Podcast: Newsmaker Edition.Oklahoma Congressman Tom Cole is a dedicated leader in the fight in Washington D.C. for sustained increases in federal funding for biomedical research through the National Institutes of Health. U.S. Rep. Cole, Chairman of the House Labor-HHS Appropriations Subcommittee, speaks candidly to Amazing Things about the promise of medical innovation, the scourge of disease and the critical importance of America's investment in biomedical research.
    23 min
  • Jean Bennett: A Gene Therapy to Treat Blindness
    Hear the story of the first gene therapy approved in the United States to target a disease caused by mutations in a specific gene. In this case, the RPE65 gene, which affects vision. For Dr. Jean Bennett, the physician scientist behind this medical breakthrough, being able to change the prognosis for people who are blind or losing their vision — and to see the profound impact that this has on their life — has been a career well spent.
    13 min
  • Amazing Things Podcast LIVE Congressional Briefing
    A special live episode of UMR's Amazing Things Podcast broadcast from Capitol Hill in Washington D.C., on Wednesday, November 15, 2017. Host Adam Belmar is joined by four NIH-funded scientists: Dr. Ed Damiano of Boston University, Dr. Natalia Trayanova of Johns Hopkins University, Dr. Vadim Backman of Northwestern University and Dr. Li-Heui Tsai of Massachusetts Institute of Technology (MIT). The program includes remarks from U.S. Rep. Fred Upton of Michigan and U.S. Rep. Mike Simpson of Idaho.
    1 hr 3 min
  • Li-Huei Tsai: A Ray of Hope in the Fight Against Alzheimer's Disease
    The statistics on Alzheimer’s disease are daunting. More than five million Americans are living with the disease and by 2050 this number could be as high as 16 million.
    Dr. Li-Huei Tsai, Picower Professor of Neuroscience at MIT, and her team of researchers have discovered that LED lights, flickering at a specific frequency, substantially reduce the beta amyloid plaques seen in Alzheimer’s disease, in the visual cortex of mice. Their work was published in the journal Nature in December 2016. If this finding bears out in humans, it is a game-changer.
    15 min
  • Natalia Trayanova: Using a Personalized, Virtual Heart to Prevent Sudden Cardiac Death
    More than 350,000 people each year will experience an out of hospital cardiac arrest. Cardiac arrest is an extremely dangerous circumstance that requires immediate treatment. In cardiac arrest, death results when the heart suddenly stops working properly. This may be caused by abnormal, or irregular, heart rhythms (called arrhythmias). Since prior heart attack, or myocardia infarction, is a major risk factor for arrhythmia, these patients are prime candidates for surgically implanted defibrillators, which monitor heart rhythm and deliver an electric shock if needed to keep the heart beating regularly.The current tools for assessing whether a patient is likely to actually suffer an arrhythmia and therefore bene t most from the defibrillator (which carries its own risks) are not highly predictive. Dr. Natalia Trayanova, the Murray B. Sachs Professor of Biomedical Engineering and Medicine at Johns Hopkins University, and a team of researchers are working to change this. They have developed a computational model for predicting which heart patients are at greatest risk for arrhythmia. Called VARP, for virtual arrhythmia risk predictor, Dr. Trayanova’s virtual heart uses MRI and other patient-specific cardiac data to create a personalized geometrical model of the heart. The model incorporates not just the wall of the heart, but also all the structural remodeling that occurs after a heart attack. That computer model, coupled with mathematical equations that express the dynamics of the human cells of the heart, is then stressed in a variety of different ways and locations to see if a patient is at risk for sudden cardiac death due to arrhythmia.
    9 min

About Amazing Things Podcast

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Meet the leaders of today’s scientific revolution, and discover the new technologies allowing scientists to understand and treat disease, improve health, and overcome impossible odds. Today, research…