• •Trade – Cordarone
• •Class – Antiarrhythmic
• •MOA - Acts directly on the myocardium to delay repolarization and increase the duration of action potential 
• •Indications – Ventricular arrhythmias, second line for atrial rhythms.
• •Contraindications – Sick sinus syndrome, second and third degree heart block, cardiogenic shock, when episodes of bradycardia have cause syncope, sensitivity to benzyl alcohol and iodine.
• •Side effects – Burning at the IV site, hypotension, bradycardia. 
• •Dosing

Ventricular Fibrillation, and Pulseless Ventricular Tachycardia 

Adult: 300mg IV/IO followed by 150mg in 3-5 mins 

        1mg/min maintenance infusion after ROSC

Pedi: 5mg/kg max dose 300mg may repeat 5mg/kg up to 15mg/kg

Stable Wide Complex Tachycardia

Adult: 150mg over 10 mins. 

Pedi: 5mg/kg IV/IO over 20-60 mins