Answers from the Lab

By Mayo Clinic LaboratoriesScience Medicine Health & Fitness

Answers from the Lab episodes

August 11, 2022 Monkeypox testing progress: Dr. Bill Morice
William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss new developments in monkeypox testing, updates on the federal response, and lessons learned from managing other viruses.
11 min
August 09, 2022 Enhanced detection of genetic mutation to optimize leukemia treatment: Rong He, M.D.
(00:32)
Could you please provide a bit about yourself and your background?
(01:39)
Could you please give a basic overview of the NPM1Q test and why we are so pleased to offer it?
(06:56)
Which patients should have this test and when should it be performed? Is it when they are initially diagnosed?
(09:44)
How would translocation 8;21 and inversion 16 tests be incorporated into testing for patients?
(10:41)
How are the results used in patient care?
(13:41)
What alternative tests options are available, and how do they compare with the NPM1Q test?
(16:22)
What considerations would you suggest clinicians keep in mind for patient care?
20 min
August 04, 2022 Operationalizing monkeypox testing: John Osborn
John Osborn, operations administrator in the Department of Laboratory Medicine and Pathology at Mayo Clinic, joins the "Answers From the Lab" podcast for a discussion with host Bobbi Pritt, M.D. about monkeypox testing. In this episode, John and Dr. Pritt discuss how Mayo Clinic swiftly operationalized monkeypox testing and the challenges involved with supporting the new assay, including staffing.
If the work discussed in the episode interests you, we’d love to have you join our team. If you are an MLS/CLS graduate or a biology/chemistry graduate, consider applying for a laboratory career with the Department of Laboratory Medicine and Pathology.
15 min
August 02, 2022 Nonradioactive assay helps diagnose heparin reaction: Rajiv Pruthi, M.B.B.S.
(01:51)
Can you give a brief overview of the assay you developed and how it works?
(06:28)
The serotonin release assay is utilized within five to 14 days of heparin exposure. Is there a subsequent time when this test would be utilized?
(10:28)
How does this assay improve upon previous approaches?
(12:58)
Is there greater specificity and sensitivity with the use of nonradioactive materials?
(13:46)
What interesting findings have we had through the process of developing and validating this assay?
16 min
July 28, 2022 Monkeypox declared a global public health emergency: Dr. Bill Morice
William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with podcast host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss the World Health Organization’s declaration of monkeypox as a global public health emergency, how Mayo Clinic Laboratories quickly implemented testing, and the public-private partnership to manage the response.
15 min
July 26, 2022 FDA-approved test expands options for Alzheimer's disease: Joshua Bornhorst, Ph.D.
(00:32)
Can you please tell our listeners a little about yourself and your background?
(01:00)
Mayo Clinic Laboratories already offers one test for Alzheimer's disease, right?
(01:32)
Could you tell our listeners about the new FDA-approved test that Mayo Clinic Laboratories will launch soon?
(02:43)
The test results will report the ratio of the amyloid isoforms, not the individual test components, right?
(03:26)
Does the new test require a certain tube?
(04:15)
Can you provide a little more detail on the commercially available tube that will be required?
(04:36)
Which patient population would benefit most from this test?
(05:30)
Can you compare and contrast the existing Alzheimer's disease test and the new amyloid ratio evaluation?
(08:58)
Is Mayo Clinic's ADEVL the only test that measures the tau component?
(09:51)
When would one of these tests be more appropriate than the other?
(10:52)
Can you help our listeners understand what a "laboratory developed" test means?
(11:43)
From a physician's standpoint, how might this new test improve patient care?
13 min
July 21, 2022 Managing the current rise in COVID cases: Dr. Bill Morice
William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with podcast host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss the science behind the increasing COVID-19 infections, why individuals can get reinfected with different variants, and the effectiveness of the at-home antigen tests.
10 min
July 14, 2022 Scaling monkeypox testing and the new COVID variant: Dr. Bill Morice
William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with podcast host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss advances in monkeypox testing, working with the CDC to scale testing and response efforts, the fast-spreading BA.5 variant of COVID-19, and how at-home testing affects the number of reported cases.
13 min
June 30, 2022 New SALSA bill and monkeypox testing at Mayo: Dr. Bill Morice
William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with podcast host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss the recent Department of Health and Human Services announcement that named Mayo Clinic Laboratories as one of five commercial labs to expand capacity for monkeypox testing. They also discuss newly introduced legislation – the Saving Access to Laboratory Services Act (SALSA).
12 min
June 23, 2022 The Latest on Monkeypox and Lab Legislation: Dr. Bill Morice
William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with podcast host Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Morice discuss what the increasing monkeypox cases are revealing, and regulatory updates on the VALID Act and PAMA.
15 min

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A Mayo Clinic curated podcast sharing Mayo Clinic knowledge and advancements on the state of testing, science, and people who are making it happen behind the scenes.