Timestamps:

Speaker 1: (01:03)
 Do you want to tell us a little bit for the listeners, what herd immunity is? 

Speaker 1: (02:49)
 With your immunology background, if you have any thoughts on what would be the ideal way in your mind?

Speaker 1: (06:21)
 So it does show the power of the immune response, but it is that question of, is it going to be antibodies? Is it going to be T cells? Is it going to be a mixture of both and can a vaccine elicit a protective response from those different branches of the immune system: cellular and humoral?

Speaker 1: (08:37)
 What do you think about other tests as far as detecting T cell responses? What do you see on the horizon? 

Resources:

COVID-19 Resource Center

Timestamps:

Speaker 2: (01:12)
 Where does it all start? 

Speaker 2: (04:32)
 How many followers have you? 

Speaker 2: (05:59)
 So what would your advice be to someone who might listen to this and want to follow in your footsteps? 

Speaker 2: (10:41)
 So you've been doing this now for a long time, 600 cases on your blog, do you have a few favorites? 

Resources:

Creepy Dreadful Wonderful Parasite Blog

Twitter: @parasitegal

Facebook: https://www.facebook.com/ParasiteGal/

01:21
 Could you give us the updates on what you see the state of testing to be today? 

01:53
 What are some of the new things on the horizon? You know, we're hearing about pooling and antigen testing. 

08:34
 What are your thoughts on that? 

Timestamps:

Speaker 1: (01:14)
 Can you tell our listeners about the state of testing today? 

Speaker 1: (05:14)
 You've been posting on Twitter, some really interesting statistics, do you want to share some of those?

Speaker 1: (09:46)
 Do you have designer masks, Bill, and do you match your outfit for the day?

Resources:
https://news.mayocliniclabs.com/covid19/

00:44
 So can you tell me a little bit about what your normal role was at Mayo Clinic before COVID happened? Then how has that changed as the COVID pandemic started and progressed? 

02:06
 So, what are some of the current challenges facing the supply chain and what have been some of Mayo Clinic’s strategies to successfully navigate through these evolving supply chain shortages and demands for supplies during the COVID-19 pandemic? 

05:51
 What are some of the innovative ways that Mayo Clinic has adjusted to overcome some supply chain shortages during the COVID-19 pandemic?

10:01
 So, Dr. Jannetto, is there anything else that you think would be of interest to our group?

Resources:
https://news.mayocliniclabs.com/covid19/

(01:01)
 Can you tell us how lab testing capacity is in general at Mayo Clinic and across the United States? 

(03:34)
 We’re trying to balance how we test for the routine stuff, in addition to meeting COVID demands? 

(04:40)
 How should we be using testing to manage this COVID-19 outbreak? 

(06:36)
 So the partnership you mentioned, do you want to tell us a little bit more about that? Because it was recently announced and not everyone may have seen those announcements with what we're doing with Delta.

Resources:
https://news.mayocliniclabs.com/covid19/

Timestamps:
Speaker 1: (01:00)
Perhaps you could start off by just telling us how is this test different than the other antibody tests? What is a neutralizing antibody to begin with? 

Speaker 1: (02:40)
 Can you tell us about the new neutralizing antibody test then and how it came about? 

Speaker 1: (03:39)
 What did you do specifically to make it a clinical test? 

Speaker 1: (04:50)
 How many tests then can be completed each day? 

Speaker 1: (05:11)
 How would you incorporate this test into the clinical workflow then? Would there first be a screen to make sure the patient has antibodies to begin with? 

Speaker 1: (06:12)
 Can you tell us a little bit about the science about how that works and how this live virus comes into play? 

Speaker 1: (08:10)
 How will this assay be used now that we have it and should everyone be tested? 

Speaker 1: (09:53)
 Do you have any idea of how many people that have antibodies, actually have neutralizing antibodies specifically? 

Speaker 1: (11:19)
 Are there other laboratories that can offer this type of testing?

Speaker 1: (13:07)
 Are there any other ways that this test could be used at this time?

Resources:
https://news.mayocliniclabs.com/covid19/

01:16 What are you thinking when you look to the future for laboratory testing for COVID-19? 

03:05 What are your thoughts on that? What would be some ways that we could predict who would be at risk for severe disease and really might go downhill quickly? 

04:47 So should we be testing for T-cells? Are there any T-cell marker tests in the future? 

05:41 Can you tell us a little bit about that from your view as our chair?

Resources:
https://news.mayocliniclabs.com/covid19/

Timestamps:

Speaker 1: (00:39)
So let's start by talking about the new neutralizing antibody test. Can you tell us a little bit about this test and how it came about? 

Speaker 1: (04:55)
 So we are screening all of the employees throughout the Mayo Clinic enterprise. Can you tell us about this and the scope and the purpose behind this program? 

Speaker 1: (07:26)
 So a lot of things to consider, I'm sure our listeners are now saying, so how did you roll it out? Or what are the plans?

Resources:
https://news.mayocliniclabs.com/covid19/

Full Show Notes (Timestamps)

Speaker 1: (00:56)
 So there continues to be a lot of interest in antibody testing for COVID-19. Can you refresh our memories on what antibody testing is? 

Speaker 1: (02:12)
 Now that we are actually six months into this outbreak, what is our understanding about using serologic testing? Will it be the magic bullet that will allow us to go back to work?

Speaker 1: (05:26)
 Can you explain that to everyone in ways that we could all understand? What does this mean exactly? How does this impact serologic testing and interpretation of results? 

Speaker 1: (09:29)
 So given this information on the positive predictive value and how it's influenced by both the prevalence and specificity of a test, have government agencies provided guidance on how to select and interpret serologic results for COVID-19?

Resources:
https://news.mayocliniclabs.com/covid19/