In today's operational climate, threats and attacks against network infrastructures have become far too common. Researchers in the SEI's CERT Division work with organizations and large enterprises, many of whom analyze their network traffic data for ongoing status, attacks, or potential attacks. Through this work we have observed both challenges and best practices as these network traffic analysts analyze incoming contacts to the network, including packets traces or flows. In this SEI Podcast, Tim Shimeall and Timur Snoke, both researchers in the SEI's CERT Division, highlight some best practices (and application of these practices) that they have observed in network traffic analysis.