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Scientists must focus on the importance of representative study samples and of engaging with diverse autism community members.
The approach, tested in mice, selectively boosts the expression of the autism-linked gene SCN1A in a subgroup of inhibitory cells.
The cells’ altered proliferation rates hint at ways to diagnose and potentially treat autism earlier.
By as early as age 2, autistic children appear to have a smaller salience network and a larger default mode network, among other differences, than children without the condition.
Neurons with a faulty copy of SETD1A, a gene tied to autism and schizophrenia, show structural abnormalities and altered connectivity patterns.
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