Audio research news

A basic scientist at heart, Hollis Cline has spent decades pushing the boundaries of what researchers can see in the brain. Her persistence has led to a deeper understanding of how some autism-linked genes influence brain development.

The paper relied on parent-reported data and adjusted for few potentially confounding variables.

Some copy number variants may boost a person’s chances of having autism, but to a lesser extent than previously thought.

Girls and young women with Rett syndrome have less severe anxiety and breathing problems after treatment with trofinetide, an analogue of insulin-like growth factor 1, according to an unpublished placebo-controlled trial.

Mice missing a copy of the gene ASH1L have excess synapses and autism-like behavioral differences, some of which are reversed by boosting an ASH1L-regulated gene.