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Spectrum’s staff couldn’t report on the ground this year — with no lab visits, sit-down interviews or in-person conferences to attend — but we observed a lot of changes from our computer screens.
The Spectrum team highlights five topics that distinguished autism research in 2020: diversity in data, gene therapies, subtyping, social circuitry and the ‘autism gene’ debate.
Mice that model 22q11.2 deletion syndrome lack social memory, but that trait can be reversed using a drug that targets the flow of potassium ions in neurons.
People with autism who carry DNA variants in the same protein-coding region of a gene have more similar cognitive abilities and behaviors than those who carry mutations in different regions of the same gene.
Some social behaviors associated with autism are heritable, but the extent to which genes and the environment influence these behaviors changes as a child grows.
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