AudioScholar Family Medicine Weekly (India)

This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice.

This week's papers:

1. Continuous Glucose Monitoring in Non-Insulin-Treated Type 2 Diabetes. — New England Journal of Medicine 2026
2. Implementing the 2023 Canadian Thoracic Society guideline on pharmacotherapy in patients with stable chronic obstructive pulmonary disease in primary care. — Canadian Family Physician 2026
3. How Would You Screen This 26-Year-Old Woman for Cervical Cancer? Grand Rounds Discussion From Beth Israel Deaconess Medical Center. — Annals of Internal Medicine 2026
4. Increasing prescribing of acetylsalicylic acid in pregnancy: Program evaluation in Saskatchewan. — Canadian Family Physician 2026
5. Comparative Effectiveness of Phenobarbital vs Diazepam for Alcohol Withdrawal Syndrome. — JAMA Internal Medicine 2026
6. The Rise of Adulterated 7-Hydroxymitragynine Kratom Products Creates Challenges for Health Care and Policy. — Journal of the American Board of Family Medicine 2026
7. Psychedelic-assisted psychotherapy: Emerging paradigm. — Canadian Family Physician 2026
8. Adult Attention Deficit-Hyperactivity Disorder. — New England Journal of Medicine 2026
9. An innovative hybrid cognitive behavioral therapy for insomnia approach to insomnia treatment: a retrospective chart review study. — Family Practice 2026
10. Delirium. — Annals of Internal Medicine 2026

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This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice.

This week's papers:

1. Smoking Cessation Among Underserved Patients Referred for Lung Cancer Screening: A Randomized Clinical Trial. — JAMA 2026
2. Evaluation of Intervention Strategies to Improve Follow-Up Colonoscopy After Abnormal FIT/FOBT Result: A Systematic Review and Meta-Analysis. — JAMA Internal Medicine 2026
3. Reclassification of office blood pressure categories according to the 2024 European Society of Cardiology guidelines and its implications for clinical practice in primary care: a cross-sectional study. — BMC Primary Care 2026
4. Advance Care Planning for Black and White Older Adults With Serious Illness: The EQUAL ACP Randomized Trial. — JAMA 2026
5. Pharmacologic Treatments for Females With Menopausal Vasomotor Symptoms: A Clinical Guideline From the American College of Physicians. — Annals of Internal Medicine 2026
6. Oral small-molecule GLP-1RA safiglipron versus dapagliflozin in type 2 diabetes: a randomized, double-blind, active-comparator-controlled phase 3 trial. — Nature Medicine 2026
7. Temporary Cessation of DMARD Therapy and COVID-19 Supplemental Dose Vaccine Immunogenicity in Patients With Inflammatory Arthritis: The COVER Randomized Clinical Trial. — JAMA Internal Medicine 2026
8. Effect of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID : An Adaptive Randomized Trial. — Annals of Internal Medicine 2026
9. Strengthening health systems to prioritise, provide care, and prevent osteoarthritis: a roadmap for global health policy. — The Lancet 2026
10. Migraine. — The Lancet 2026

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This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice.

This week's papers:

1. Retatrutide, a Triple Hormone Receptor Agonist, for Treatment of Obesity. — New England Journal of Medicine 2026
2. Survodutide Once Weekly in Adults with Obesity and Type 2 Diabetes. — New England Journal of Medicine 2026
3. Cardiovascular safety of orforglipron versus insulin glargine in adults with type 2 diabetes at increased cardiovascular risk (ACHIEVE-4): a phase 3, event-driven, randomised, open-label, non-inferiority, active comparator trial. — The Lancet 2026
4. Effects of semaglutide on kidney disease in type 2 diabetes: a randomized placebo-controlled trial. — Nature Medicine 2026
5. Association between overweight and obesity and the frequency of general practice consultations among children aged 2-17 years: a French retrospective cohort study. — BJGP Open 2026
6. Histologic Features and Clinical Outcomes of Lean Metabolic Dysfunction-Associated Steatotic Liver Disease. — JAMA 2026
7. 8 weeks versus 12 weeks of sofosbuvir-velpatasvir for treatment-naive, non-cirrhotic, chronic hepatitis C (RESOLVE): a multicentre, open-label, non-inferiority, randomised controlled trial in India. — The Lancet 2026
8. The burden and long-term outcomes of diagnosed and underdiagnosed COPD across diverse communities from high-income, middle-income, and low-income countries: the Prospective Urban Rural Epidemiology (PURE) study. — The Lancet Global Health 2026
9. Irritable bowel syndrome. — Nature Reviews Disease Primers 2026

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This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice.

This week's papers:

1. Contemporary menopausal hormone therapy and thrombotic disease: nationwide nested case-control study. — BMJ 2026
2. QTc changes and early major adverse cardiovascular events associated with antidepressant treatment for major depressive disorder in adults: individual participant data network meta-regression of double blind randomised trials. — BMJ 2026
3. Impact of new guidelines for microbiological sampling on antibiotic prescribing patterns in general practice in the North Denmark Region: a retrospective pre-post observational study. — Scandinavian Journal of Primary Health Care 2026
4. Faecal microbiota transplantation in irritable bowel syndrome (REFIT2): a randomised, double-blind, placebo-controlled, phase 3 trial. — The Lancet 2026
5. Which aspects of continuity of care in primary care are associated with better self-rated health? A cross-sectional study among older adults in Berlin. — BMC Primary Care 2026
6. Chest auscultation - tradition and expectations Concerns and promises in the era of smart stethoscopes. — Scandinavian Journal of Primary Health Care 2026
7. Clinical Uses of Common Genetic Variants Associated with Common Diseases. — New England Journal of Medicine 2026

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Welcome to This Week in Family Medicine. This week we're covering 10 notable papers spanning cancer detection and surveillance, reproductive and allergy prevention trials, and the broader questions of sleep, global cardiometabolic inequity, and how we explain — and increasingly automate — the primary care consultation. Let's dive in.

This week's papers:

1. Colonoscopy Intervals and Colorectal Cancer Incidence after Adenoma Removal. — New England Journal of Medicine 2026
2. Intrauterine Mepivacaine Instillation vs Placebo for Pain During IUD Placement: A Randomized Clinical Trial. — JAMA 2026
3. Trial of a Maternal Diet Rich in Eggs and Peanuts to Reduce Infant Allergy. — New England Journal of Medicine 2026
4. Blood test trend versus single threshold abnormality to discriminate cancer from non-cancer in patients with unexpected weight loss: A retrospective cohort study. — PLOS Medicine 2026
5. Global inequalities in cardiometabolic care and achievable cardiovascular risk reduction by wealth, region, and sex: a pooled analysis of individual participant data from 76 countries. — The Lancet Global Health 2026
6. Explaining symptoms in general practice: a predictive processing framework for primary care consultations. — Scandinavian Journal of Primary Health Care 2026
7. Misaligned by design: evaluating and deploying generative AI for the real-world conditions of primary care: a Nordic and European perspective. — Scandinavian Journal of Primary Health Care 2026
8. Accelerometer-derived real-world sleep stages and risk of incident diseases: A UK Biobank cohort study and phenome-wide association analysis. — PLOS Medicine 2026
9. Precision prevention and early detection: framework for a new clinical cancer control pathway. — The Lancet 2026
10. Switch to injectable cabotegravir-rilpivirine given every 8 weeks in adolescents living with HIV with virological suppression in sub-Saharan Africa (LATA): a randomised, open-label, multicentre, 96-week non-inferiority trial. — The Lancet 2026

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Welcome to This Week in Family Medicine. This week we're covering 9 notable papers spanning prescribing safety and risk prediction in the older and chronically ill, acute presentations in the office — chest pain, skin infections and poisoning — and a set of papers on how we communicate, treat and immunise. Let's dive in.

This week's papers:

1. Exploring high priority potentially inappropriate prescribing cascades in older adults: population level retrospective cohort study. — BMJ 2026
2. Simultaneous derivation, validation, and comparison of predictor hazard ratios for cardiovascular risk prediction equations in patients with diabetes from high versus non-high income countries: cohort study. — BMJ 2026
3. Rheumatoid Arthritis in Adults: A Review. — JAMA 2026
4. Ruling out acute coronary syndrome in primary care: a diagnostic trial (POB-HELP). — British Journal of General Practice 2026
5. Advances in the diagnosis and management of skin and soft tissue infections. — BMJ 2026
6. Toxidromes. — Nature Reviews Disease Primers 2026
7. Influence of Physician Behaviors on How Patients Interpret Normal Test Results. — Annals of Family Medicine 2026
8. Immunogenicity of fractional one-fifth and one-half doses of 17DD yellow fever vaccine compared with full dose in children aged 9-23 months in Uganda: a phase 4, single-blind, randomised clinical trial. — The Lancet 2026
9. Inhaled siRNA therapy targeting RAGE for pulmonary inflammation: a first-in-human randomized trial. — Nature Medicine 2026

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Welcome to This Week in Family Medicine. This week we're covering 10 notable papers spanning respiratory and herpesvirus vaccination, cancer care in general practice, and a set of papers about the workforce, the evidence we read, and the medicines we prescribe. Let's dive in.

This week's papers:

1. COVID-19 Vaccine Effectiveness and Safety for the 2026-2027 Respiratory Season. — JAMA 2026
2. Influenza Vaccine Effectiveness and Safety for the 2026-2027 Respiratory Season. — JAMA 2026
3. Primary care quality and secondary healthcare utilisation in patients with multimorbidity: a retrospective cohort study. — British Journal of General Practice 2026
4. A systematic review of behavioural interventions for prevention of recurrent urinary tract infections. — BJGP Open 2026
5. A primary care intervention to expedite cancer diagnosis: protocol for the ThinkCancer! phase III trial. — BJGP Open 2026
6. The role of general practitioners in German cancer care: a scoping review. — BMC Primary Care 2026
7. Varicella zoster virus infection. — Nature Reviews Disease Primers 2026
8. Large Language Model versus Clinician Written Summaries of Research Papers. — Journal of the American Board of Family Medicine 2026
9. The Impact of Biases for Early-Career Women in Medicine: "It's the Little Day-to-Day Microaggressions". — Journal of the American Board of Family Medicine 2026
10. (Un)intended consequences of mass-prescribing GLP-1s. — Science 2026

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Welcome to This Week in Family Medicine. This week we're covering seven notable papers spanning cardiovascular prevention and deprescribing, digital tools for changing patient and prescriber behaviour, and the evidence base underpinning contested clinical guidelines. Let's dive in.

This week's papers:

1. Discontinuation of β-blockers in stable patients with previous myocardial infarction, preserved left ventricular ejection fraction, and no heart failure: a pooled analysis of individual patient data. — The Lancet 2026
2. Anticoagulation for Atrial Fibrillation with Intermediate Stroke Risk. — New England Journal of Medicine 2026
3. Digital Outreach to Improve Statin Refills in Patients With Low Statin Adherence: The ADHERE-ASCVD Randomized Clinical Trial. — JAMA 2026
4. Specialist Referral for Cardiovascular Risk in Patients With Prostate Cancer: A Randomized Clinical Trial. — JAMA Internal Medicine 2026
5. Safety and efficacy of the 0/1 h pathway for myocardial infarction in the emergency department: an international, pragmatic, stepped-wedge, cluster-randomised, controlled trial. — The Lancet 2026
6. Systematic reviews and the needs of the adolescent transgender health care field. — The Lancet 2026
7. Adherence to smartphone-delivered antimicrobial prescribing guidelines in hospitals in Lao PDR: A stepped-wedge cluster randomized controlled trial. — PLOS Medicine 2026

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Welcome to This Week in Family Medicine. This week we're covering nine notable papers spanning updated guidance on common chronic conditions, the uncomfortable question of how payment and oversight systems shape our prescribing, and new evidence on delivering care digitally, mobile, and across the hospital-to-community divide. Let's dive in.

This week's papers:

1. Adult Overweight and Obesity Management: Updates From the 2025 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guidelines — Annals of Internal Medicine 2026
2. Postural Orthostatic Tachycardia Syndrome (POTS): A Review — JAMA 2026
3. Diagnosis and management of acute hyperkalaemia — BMJ 2026
4. General practitioners' type of remuneration and antibiotic prescriptions. An analysis of patient switches using nationwide registry data — Scandinavian Journal of Primary Health Care 2026
5. HATCHing plans: a qualitative study of how discharge communication can support expert generalist management — BJGP Open 2026
6. Effect of a digital intervention on mental health symptoms in adults with chronic conditions: A three-arm randomized controlled trial — PLOS Medicine 2026
7. Opioid prescribing after Joint Commission hospital accreditation inspections: quasi-experimental analysis — BMJ 2026
8. Assessing the reliability and validity for metabolic syndrome diagnosis using point-of-care analyzers in a mobile setup - a pilot study — BMC Primary Care 2026
9. Public primary healthcare service network planning in Finland: a document analysis of principles, justifications, and future directions — Scandinavian Journal of Primary Health Care 2026

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Welcome to This Week in Family Medicine. This week we're covering nine notable papers spanning diagnostic restraint and overtreatment in primary care, prevention gaps in the populations we serve least well, and new evidence on integrating and scaling care for chronic disease and mental health. Let's dive in.

This week's papers:

1. Management of Shoulder Pain in Primary Care: A Review — JAMA Internal Medicine 2026
2. Serologic Immunity to Hepatitis A and B in US Adults and High-Risk Populations — JAMA Internal Medicine 2026
3. Out-of-hours C-reactive protein point-of-care testing and its association with long-term healthcare-seeking — Scandinavian Journal of Primary Health Care 2026
4. Evidence-Based Tobacco-Cessation Strategies for Low- and Middle-Income Countries — New England Journal of Medicine 2026
5. Effectiveness of a scalable, remotely delivered stepped-care intervention for psychological distress among Polish migrant workers in the Netherlands: The RESPOND randomised controlled trial — PLOS Medicine 2026
6. Methicillin-resistant Staphylococcus aureus — Nature Reviews Disease Primers 2026
7. A randomized, placebo-controlled trial of 13-valent pneumococcal conjugate vaccination to accelerate immune recovery after sepsis — Science Translational Medicine 2026
8. Integrating hypertension care into the existing HIV services package in Botswana (InterCARE): a pair-matched, cluster-randomised, type 2 hybrid effectiveness-implementation trial — The Lancet Global Health 2026
9. Avoidable mortality, clinical outcomes and determinants of premature death among adults with severe or profound intellectual disability: A population-based analysis of mortality data in England — PLOS Medicine 2026

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