AudioScholar Family Medicine Weekly (India)

Welcome to This Week in Family Medicine. This week we're covering notable papers spanning global public health, new therapeutic interventions for chronic disease, and a look at foundational science that may shape future practice. Let's dive in.

This week's papers:

1. Estimates of global causes of death for children and adolescents aged 5-19 in 2000-24: secondary data analysis using bayesian multinomial logistic regression. — BMJ (Clinical research ed.) 2026
2. Global, regional, and national impact of the Expanded Programme on Immunization against 14 pathogens from 1974 to 2024: an economic evaluation. — The Lancet. Global health 2026
3. Spermine is an endogenous iron chelator that inhibits ferroptosis. — Nature 2026
4. Acquired genetic and cell-state changes in IDH-mutant glioma progression. — Nature 2026
5. LASER couples damage sensing to ESCRT assembly for lysosome repair. — Nature 2026
6. Assessing quality of childbirth care provided by skilled health personnel in Exemplar countries. — Nature medicine 2026
7. Medically tailored meals receipt and healthcare utilization and costs in Massachusetts' Medicaid demonstration. — Nature medicine 2026
8. Efficacy and safety of ocrelizumab in primary progressive multiple sclerosis, including older patients and those with more advanced disease (ORATORIO-HAND): a multicentre, double-blind, randomised, placebo-controlled, phase 3b study. — Lancet (London, England) 2026
9. One-Year Mortality Among Opioid Overdose Survivors. (Abstract not provided) — JAMA 2026

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Welcome to This Week in Family Medicine. This week we're covering 9 notable papers spanning the evolving challenges of primary care practice, new frontiers in disease screening and treatment, and a look at global health trends. Let's dive in.

This week's papers:

1. Phase 3 Results of Bepirovirsen Treatment for Chronic Hepatitis B Virus Infection. — The New England journal of medicine 2026
2. Fibroblast growth factor receptor inhibition for succinate dehydrogenase-deficient gastrointestinal stromal tumors: a phase 2 trial. — Nature medicine 2026
3. Medication Management Among Older Adults Living Alone With Cognitive Impairment. — JAMA internal medicine 2026
4. CRT-Estimands Framework: consensus based extension of the ICH E9(R1) addendum for cluster randomised trials. — BMJ (Clinical research ed.) 2026
5. Updated trends in the global prevalence and burden of mental disorders, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023. — Lancet (London, England) 2026
6. Screening Children for Early-Stage Type 1 Diabetes. — JAMA 2026
7. More Indirect Patient Care Activities per Visit: 11-Year Analysis of Family Physician Electronic Health Records in Canada. — Annals of family medicine 2026
8. Primary care practitioners' perspectives on medicine optimisation for older people from ethnic minorities with polypharmacy in primary care: a realist evaluation. — BJGP open 2026
9. Cost of health systems strengthening for small and sick newborn care in four sub-Saharan African countries implemented with NEST360: incremental cost analyses. — The Lancet. Global health 2026

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Welcome to This Week in Family Medicine. This week we're covering 9 notable papers spanning large-scale prevention and screening, new insights into disease biology, and a look at the very foundations of our practice, from clinical trials to healthcare delivery. Let's dive in.

This week's papers:

1. CRT-Estimands Framework: consensus based extension of the ICH E9(R1) addendum for cluster randomised trials. — BMJ (Clinical research ed.) 2026
2. Screening Children for Early-Stage Type 1 Diabetes. — JAMA 2026
3. Mitochondrial L-2-hydroxyglutarate is a physiological signalling metabolite. — Nature 2026
4. Dopamine drives persistent remodelling of the maternal brain. — Nature 2026
5. Advancing Indigenous Health Equity in Medical School Curricula. — The New England journal of medicine 2026
6. Brain morphology in Anorexia Nervosa and its subtypes: A multi-cohort study of individual participant data. — PLoS medicine 2026
7. Primary Care as a Public Utility: The Case for a Common Fund. — JAMA 2026
8. Population-scale genomic medicine with the Hong Kong Genome Project. — Nature medicine 2026
9. Prepregnancy Care and Counseling: A Review. — JAMA 2026

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Welcome to This Week in Family Medicine. This week we're covering 10 notable papers spanning the long-term consequences of viral infections, the expanding scope of health guidelines to include public and planetary health, and new insights into foundational pillars of wellness like sleep and mental health. Let's dive in.

This week's papers:

1. Post-traumatic stress disorder. — Nature reviews. Disease primers 2026
2. Sleep chart of biological ageing clocks in middle and late life. — Nature 2026
3. D-SPIN constructs regulatory network models from scRNA-seq that reveal organizing principles of perturbation response. — Cell 2026
4. Ensitrelvir for Covid-19 Postexposure Prophylaxis in Household Contacts. — The New England journal of medicine 2026
5. Integrating Planetary Health in Health Guidelines (GRADE Guidance 46). — Annals of internal medicine 2026
6. Self-Collected HPV Testing for Cervical Cancer Screening-Responsible Implementation to Reduce Disparities. — JAMA internal medicine 2026
7. Implementing sustainable liver health in Europe: a second EASL-Lancet Commission. — Lancet (London, England) 2026
8. Changes in Mifepristone Use at Pharmacies After Removal of the FDA In-Person Dispensing Requirement. — JAMA 2026
9. Respiratory viral infections prime accelerated lung cancer growth. — Cell 2026
10. Immune-microbiome coordination defines interferon setpoints in healthy humans. — Cell 2026

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