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Authentic Biochemistry
Authentic Biochemistry episodes
- CytoEpigenetics XII. The central role of mitochondria in regulating cell fate and metabolic switching is necessary and universal in epigenetic modification of gene expression. DJGPhD.20.5.22
References
Dr Guerra's lecture notations and synthesis
Cell. 2014 Dec 18; 159(7): 1615–1625
Nat Commun. 2020; 11: 102.
30 min - CytoEpigenetics XI. The interactive intermediary metabolic architectonic of methylation and acetylation in epigenetic mediation of gene expression between the mitochondria and nucleus. DJGPhD.17.5.22
References
Dr Guerra's lecture notes
Nat Commun. 2020; 11: 102.
Cold Spring Harb Perspect Biol. 2013 Sep; 5(9): a017947.
30 min - CytoEpigenetics X. The IDH isofrom roles of mutant, hypoxic and constitutive activities mediate DNA, RNA and Histone3 Lys methylation patterns thus redirecting gene expression.DJGPhD.15.5.22
References
Dr Guerra's letures/reasoning
SCIENCE ADVANCES • 22 May 2019 • Vol 5, Issue 5
Cell MetabolismVolume 22, Issue 2, 4 August 2015, Pages 304-311
Cell Chem Biol. 2020 May 21; 27(5): 538–550.e7.
30 min - Cytoepigenetics IX. c-MYC controls transcription of two dehydrogenases that alter the ratio of 2-HG/alphaKG thus controling epigenetic signatures on DNA and RNA in a cancer mouse model.DJGPhD.11May22
References
Dr Guerra's Lecture notes
Cell Chem Biol. 2020 May 21; 27(5): 538–550.e7
Circulation. 2020 Dec 15;142(24):2356-2370
30 min - CytoEpigenetics VIII. The epigenetic processors, TET and BRD4, mediate control over fatty acid oxidation, pyruvate metabolism, the electron tranport chain and OXPHOS. DJGPhD.8May22. Authentic Biochem
References
Dr Guerra's notes
Circulation. 2020 Dec 15;142(24):2356-2370
Cancer Science June 2014. 105(9)
26 min - Cytoepigenetics VIIB. Warburg glycolysis explained from an epigenetic perspective plus some details of DNA methylation/demethylation. DJGPhD. Authentic Biochemistry Podcast 06May2022
References
Dr. Guerra's notes
Cancer Res. 2011 May 1; 71(9): 3400–3409
Front. Neurosci., 17 May 2017
30 min - Cytoepigenetics VIIa. Micro RNA control over the electron transport chain and oxidative phosphorylation via binding to nuclear and mitochondrial transcripts. DJGPhD03.may 2022. Authentic Biochemistry
References
Dr Guerra's pathbiochemistry lecture notes
Cancer Res. 2011 May 1; 71(9): 3400–3409
22 min - CytoEpigenetics V!. The 'magmatic' alteration of nuclear and mitochondrial gene expression via microRNA processing and translocalization is under bioenergetic control. DJGPhD. 2 May 2022.
References
Radiol Oncol. 2021 Dec; 55(4): 379–392
30 min - Cytoepigenetics V. Small interfering and micro RNA mediate mitochondrial and nuclear transcripts thus rendering cell fate, bioenergetics, and immunogenicity. DJGPhD.29.4.22. Authentic Biochemsitry
References
Guerra lecture notes/ideas
Genes (Basel). 2014 Dec; 5(4): 865–886.
Molecular Therapy—Nucleic Acids (2015) 4, e252
Int. J. Mol. Sci. 2016, 17(5), 719
30 min - Cytoepigenetics IV. Using Raman and IR spectroscopy to analyze the physical chemistry of pyrimidine nucleotide methylation. Dr. Daniel J. Guerra. 26.4.22. Authentic Biochemistry Podcast Productions
References
J of Computational Chemistry 2011 Volume32, Issue10: Pages 2077-2083
30 min
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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.